Ka's Meds

Drug Ordered Route, Dose, Frequency ---------------------------Generic Name

Classification ----------------------------------Possible Routes of Administration

Albuterol sulfate Nebulized, 2.5mg (0.5 ml) with 2ml NS, Q4hours

Bronchodilator

Salbutamol sulfate

Inhalation, IM, PO

Vancomycin IV, 600mg (120ml), Q8H2

Antibiotic

PO, IV

Pulmozyme Inhaled, 2.5mg (2.5ml), HS

Respiratory Tract Drug

Dornase alfa

Inhaled

Usual Dosage

Actions and Uses For Your Patient

2.5 mg tid or qid

To treat bronchospasm in exacerbation of cystic fibrosis: relaxes bronchial smooth muscle by stimulating beta 2 receptors Infection with MRSA: hinders bacterial wall synthesis damaging the bacterial wall membrane

Tremor, nervousness, headache, hyperactivity, tachycardia, palpitations, nausea, vomiting Fever, Pain, Hypotension, Thrombophlebitis at IV site, tinnitus, nephrotoxicity, Redman’s syndrome

To improve pulmonary function and decreases frequency of moderate to sever respiratory tract infections in CF: hydrolyzes DNA in sputum of CF causing decreased viscosity and elasticity of pulmonary secretions

CP, pharyngitis, voice alteration, rash

15mg/kg every 8 hours(per Children’s CF exacerbation protocol); 444 mg for patient

2.5 mg once daily

1

Major Side Effects

Nursing Implications

IV Rate of Administra tion

Albuterol may decrease sensitivity of spirometry used for dx of asthma, advise of possible side effects Use with caution in patients using other neurotoxic, nephrotoxic, ototoxic drugs; Hearing evaluation and renal function before starting treatment; Premedicate with Benadryl for Redman’s syndrome Don’t mix with other drugs in the nebulizer; Discard cloudy and discolored solution

Dilute in 200 ml NS and infuse over 60 minutes

Drug Ordered Route, Dose, Frequency ---------------------------Generic Name

Classification ----------------------------------Possible Routes of Administration

Merrem IV IV, 600mg (30ml), Q8H6

Antibiotic

Meropenem

IV

Tobramycin sulfate IV, 380mg (76ml), Q24H14

Aminoglycoside antibiotic IV, Inhaled

Azithromycin PO, 250mg, M/W/F

Usual Dosage

20mg/kg (per Children’s CF exacerbation protocol); 590mg for patient

Used in CF patients for treatment of Pseudomonas: inhibits cell wall synthesis in bacteria

10-12mg/kg every 24 hours (per Children’s CF exacerbation protocol); 295mg- 354mg for patient

Used to manage CF patients with Pseudomonas

Macrolide AB

Used to treat acute bacterial worsening of chronic lung disease by certain organisms

IM, PO

Zyrtec PO, 5mg, Daily Cetirizine

Antihistamine

Actions and Uses For Your Patient

5-10mg daily

Allergic rhinitis

PO

2

IV Rate of Administra tion

Major Side Effects

Nursing Implications

Seizures, HA, phlebitis, thrombophlebiti s, N/V/D, constipation, pseudomembra nous colitis, candiadis, glossitis, hematuria, apnea, dyspnea Ototoxicity, HA, lethargy, confusion, fever, seizures, N/V/D, nephrotoxicity

Obtain specimen for C&S before starting; make sure no hypersensitivity to B lactams before starting; stop drug if allergic reaction occurs; monitor for S/S superinfection

Infuse over 1530 minutes

Obtain specimen for C&S before starting; Renal function test and hearing test should be done before starting

Dilute in 50 to 100ml NS; infuse over 2060 minutes

N/V/D, abdominal pain, dizziness, vertigo, HA, fatigue, pseudomembra nous colitis, candiadis, rash, photosensitivity Somnolence, fatigue, dizziness, HA, pharyngitis, dry mouth, N/V, abdominal distress

Obtain specimen for C&S before starting; monitor for S/S superinfection

Stop 4 drug days before patient undergoes skin test

Drug Ordered Route, Dose, Frequency ---------------------------Generic Name

Prednisone PO, 20mg, Daily

Classification ----------------------------------Possible Routes of Administration

Corticosteroid PO, IV, IM

Voriconazole PO, 100mg, BID

Antifungal

VFEND

PO, IM

Usual Dosage

Actions and Uses For Your Patient

Major Side Effects

Nursing Implications

0.14mg2mg/kg daily; 4.13- 58 mg daily for patient

Decrease airway inflammation: action not clearly defined, believes it works by stabilizing leukocyte lysosomal membranes, suppresses immune response

Euphoria, insomnia, peptic ulceration, susceptibility to infections, growth suppression, cushingoid state, hypoglycemia

100mg q 12 hours

Invasive aspergillosis; serious infections caused by fungus

Fever, HA, hallucinations, dizziness, tachycardia, HTN, hypotension, N/V/D, abdominal pain, rash, chills

Always adjust to lowest effective dose,determine first if patient is sensitive to other corticosteroids, most adverse reactions are dose-dependent, monitor weight gain, diabetic patient may need to adjust insulin Monitor liver and renal function

3

IV Rate of Administra tion