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Page 1. Table of Content ( kamo nay himo ana ly)

Part I

A. INTRODUCTION (Rationale)

Most people do not think about the safety of their food until they or someone they know becomes ill from a food-related infection. As the spectrum of foodborne diseases constantly changes, there are many opportunities for food to become contaminated as it is produced and prepared. More than 250 different foodborne diseases have been described: most are infections caused by various bacteria, viruses, and parasites – e.g. Salmonella, E. coli O157:H7, Campylobacter, Norwalk-like virus, Cryptosporidium and many others. Poisoning may also result from harmful toxins or chemicals that have contaminated food.

Foodborne illnesses are infections or irritations of the gastrointestinal (GI) tract caused by food or beverages that contain harmful bacteria, parasites, viruses, or chemicals. The GI tract is a series of hollow organs joined in a long, twisting tube from the mouth to the anus. Common symptoms of foodborne illnesses include vomiting, diarrhea, abdominal pain, fever, and chills. Most foodborne illnesses are acute, meaning they happen suddenly and last a short time, and most people recover on their own without treatment. Rarely, foodborne illnesses may lead to more serious complications.

Raw foods from animals are most likely to be contaminated – beef, chicken, eggs, unpasteurized milk and cheese, and raw shellfish. Fruits and vegetables eaten raw are also of concern because they may be processed in unsanitary conditions. Most foodborne contamination is only discovered after people have suffered the effects: nausea, vomiting, abdominal cramps, diarrhea or more serious symptoms such as a high fever, blood in the stool, or prolonged vomiting. Fortunately,

techniques for tracing outbreaks, quickly finding the source of infection and correcting the cause of the outbreak are constantly improving, in a world that increasingly shares food products.

B. OBJECTIVES: The main objective of this Analytical Term Paper is to raise awareness about foodborne illness and its impacts. This specifically answer to the following: 1. Who gets foodborne illnesses? 2. What are the symptoms of foodborne illnesses? 3. When should people with foodborne illnesses see a health care provider? 4. How are foodborne illnesses treated? 5. How are foodborne illnesses prevented?

Keywords (kamo na pangita sa mga words and definition of terms ly) example Illness Foodborne Virus Bacteria Etc….

Part II. Article/ Case

Foodborne, food related illness and role of the healthcare professionals Justine Bold1 and Kamran Rostami2 Author information Copyright and License information Disclaimer This article has been cited by other articles in PMC. Foodborne infection is a major health issue and its impact on global social and economic development remains unknown (1). A paper published in the journal Nature estimates 30% of all infections over the last 60 years were Foodborne (2). The Centre for Disease Control in the United States estimates that 76 million people per year are affected by Foodborne illness, with 300,000 requiring hospital treatment and 5000 fatalities (3). Specific foods are associated with specific Foodborne infections and food poisoning (3). Examples include unpasteurised milk (Campylobacter); shellfish (noroviruses); unpasteurized apple cider (Escherichia coli O157:H7), raw and undercooked eggs (Salmonella); fish (ciguatera poisoning); raspberries (Cyclospora); strawberries (hepatitis A virus); and readyto-eat meats (Listeria). In clinical practice, healthcare professionals, including physicians, have to interpret clinical symptoms; enabling correct diagnosis and the differentiation of Foodborne illness from food allergy and intolerance, celiac disease, the irritable bowel syndrome, inflammatory bowel disease, viral infection and malignancy (4). An up to date understanding of diagnostic testing is fundamental to the identification of a food related illnesses. Obasanjo published a review in Medscape (5) that summarises the key aspects of the primer published in 2001 by the Foodborne Illness Primer Work Group (FIPWG) and its subsequent updates published in Morbidity and Mortality Weekly Reports (MMWR) (6). The article highlights that in routine clinical practice it is important to maintain good communication between

physicians, local testing laboratories and public health authorities. The review reports that most laboratories limit stool culture to screening for species such as Salmonella, Shigella, Campylobacter jejuni or E. coli. Laboratories require advanced notification if Yersinia, Vibrio, E Coli 0157:H7 or other Campylobacter species are suspected, because additional media and incubation conditions are required. Special laboratory procedures are also required to identify infection due to parasites such as Cryptosporidium and Cyclospora cayetanensis. In practice, this means physicians need to communicate with their local laboratories to ensure that arrangements for specialist testing are in place prior to the sending of samples. Furthermore public health authorities need a close relationship with local laboratories to provide advice regarding local antibiotic sensitivities and to initiate community investigation of outbreak sources. Electronic request, information technology, eLearning, etc., have become synonyms or replacements for new and different types of communication. Although new models of communication have added a litany of words to our vocabulary and created novel ways to highlight tasks and develop plans, the way we communicate has become more complicated and potentially more confusing. Maintaining good communication is a necessity within each clinical setting and across clinical speciliaties. The paper by Obasanjo serves as a reminder that knowledge about rarer conditions can aid differential diagnosis. Specific considerations are required when investigating Foodborne infections in severely ill patients, immunocompromised patients, those with a significant travel history or in those who fail to respond to empiricial treatment. Identifying the underlying Foodborne infection may necessitate repeating stool cultures, reviewing histology results and serology. Obasanjo reminds us that physicians need be aware of unusual symptoms and signs such as rashes, myalgia, arthralgia and focal neurological weakness (5). Neurological signs such as meningism or orofacial weakness may indicate life-threatening diagnoses such as Botulism, seafood contamination, mushroom poisoning or chemical poisoning (e.g. organophosphates). The review also highlights that treatment of Foodborne microbial infections with antibiotics needs to be considered carefully and should be based upon evidence of appropriateness of treatment, antimicrobial susceptibility tests as well as interpretation of signs, symptoms and results of stool microscopy/culture.

Antibiotics have no effect upon viral infections such as the common head cold and only about 5-10% of bronchitis cases are caused by a bacterial infection. Misuse and overuse of antibiotics has serious effects on public health. Antibiotic resistant bacteria are a growing threat and becoming increasingly common. Unfortunately, the low threshold of using antibiotics, in certain countries in the Middle East, might create multi-antibiotic resistant life threatening infections or "super bugs" (7). Antibiotic abuse also places the patient at unnecessary risk of adverse effects of antibiotics. Judicial use of antibiotics is therefore recommended. In conclusion, healthcare professionals play a key role in the identification and treatment of Foodborne illness. Awareness of algorithms for the correct diagnosis of food related enteropathies, good communication with testing laboratories and prompt case reporting to public health authorities are essential. Awareness on the limited benefits of antibiotics therapy should also be a priority to prevent the development of antibiotic resistant “superbugs.”

Part III. Article

Foodborne Illnesses What are foodborne illnesses? Foodborne illnesses are infections or irritations of the gastrointestinal (GI) tract caused by food or beverages that contain harmful bacteria, parasites, viruses, or chemicals. The GI tract is a series of hollow organs joined in a long, twisting tube from the mouth to the anus. Common symptoms of foodborne illnesses include vomiting, diarrhea, abdominal pain, fever, and chills. Most foodborne illnesses are acute, meaning they happen suddenly and last a short time, and most people recover on their own without treatment. Rarely, foodborne illnesses may lead to more serious complications. Each year, an estimated 48 million people in the United States experience a foodborne illness. Foodborne illnesses cause about 3,000 deaths in the United States annually.1

What causes foodborne illnesses? The majority of foodborne illnesses are caused by harmful bacteria and viruses.2 Some parasites and chemicals also cause foodborne illnesses. Bacteria Bacteria are tiny organisms that can cause infections of the GI tract. Not all bacteria are harmful to humans. Some harmful bacteria may already be present in foods when they are purchased. Raw foods including meat, poultry, fish and shellfish, eggs, unpasteurized milk and dairy products, and fresh produce often contain bacteria that cause foodborne illnesses. Bacteria can contaminate food—making it harmful to eat—at any time during growth, harvesting or slaughter, processing, storage, and shipping. Foods may also be contaminated with bacteria during food preparation in a restaurant or home kitchen. If food preparers do not thoroughly wash their hands, kitchen utensils, cutting boards, and other kitchen surfaces that come into contact with raw foods, cross-contamination— the spread of bacteria from contaminated food to uncontaminated food—may occur. If hot food is not kept hot enough or cold food is not kept cold enough, bacteria may multiply. Bacteria multiply quickly when the temperature of food is between 40 and 140 degrees. Cold food should be kept below 40 degrees and hot food should be kept above 140 degrees. Bacteria multiply more slowly when food is refrigerated, and freezing food can further slow or even stop the spread of bacteria. However, bacteria in refrigerated or frozen foods become active again when food is brought to room temperature. Thoroughly cooking food kills bacteria. Many types of bacteria cause foodborne illnesses. Examples include 

Salmonella, a bacterium found in many foods, including raw and undercooked meat, poultry, dairy products, and seafood. Salmonella may also be present on egg shells and inside eggs.



Campylobacter jejuni (C. jejuni), found in raw or undercooked chicken and unpasteurized milk.



Shigella, a bacterium spread from person to person. These bacteria are present in the stools of people who are infected. If people who are infected do not wash their hands thoroughly after using the bathroom, they can contaminate food that they handle or prepare. Water contaminated with infected stools can also contaminate produce in the field.



Escherichia coli (E. coli), which includes several different strains, only a few of which cause illness in humans. E. coli O157:H7 is the strain that causes the most severe illness. Common sources of E. coli include raw or undercooked hamburger, unpasteurized fruit juices and milk, and fresh produce.



Listeria monocytogenes (L. monocytogenes), which has been found in raw and undercooked meats, unpasteurized milk, soft cheeses, and ready-to-eat deli meats and hot dogs.



Vibrio, a bacterium that may contaminate fish or shellfish.



Clostridium botulinum (C. botulinum), a bacterium that may contaminate improperly canned foods and smoked and salted fish.

Viruses Viruses are tiny capsules, much smaller than bacteria, that contain genetic material. Viruses cause infections that can lead to sickness. People can pass viruses to each other. Viruses are present in the stool or vomit of people who are infected. People who are infected with a virus may contaminate food and drinks, especially if they do not wash their hands thoroughly after using the bathroom. Common sources of foodborne viruses include 

food prepared by a person infected with a virus



shellfish from contaminated water



produce irrigated with contaminated water

Common foodborne viruses include 

norovirus, which causes inflammation of the stomach and intestines



hepatitis A, which causes inflammation of the liver

Parasites Parasites are tiny organisms that live inside another organism. In developed countries such as the United States, parasitic infections are relatively rare. Cryptosporidium parvum and Giardia intestinalis are parasites that are spread through water contaminated with the stools of people or animals who are infected. Foods that come into contact with contaminated water during growth or preparation can become contaminated with these parasites. Food preparers who are infected with these parasites can also contaminate foods if they do not thoroughly wash their hands after using the bathroom and before handling food. Trichinella spiralis is a type of roundworm parasite. People may be infected with this parasite by consuming raw or undercooked pork or wild game. Chemicals Harmful chemicals that cause illness may contaminate foods such as 

fish or shellfish, which may feed on algae that produce toxins, leading to high concentrations of toxins in their bodies. Some types of fish, including tuna and mahi mahi, may be contaminated with bacteria that produce toxins if the fish are not properly refrigerated before they are cooked or served.



certain types of wild mushrooms.



unwashed fruits and vegetables that contain high concentrations of pesticides.

Question no. 1. Who gets foodborne illnesses? Anyone can get a foodborne illness. However, some people are more likely to develop foodborne illnesses than others, including 

infants and children



pregnant women and their fetuses



older adults



people with weak immune systems

These groups also have a greater risk of developing severe symptoms or complications of foodborne illnesses. Question no. 2. What are the symptoms of foodborne illnesses? Symptoms of foodborne illnesses depend on the cause. Common symptoms of many foodborne illnesses include 

vomiting



diarrhea or bloody diarrhea



abdominal pain



fever



chills

Symptoms can range from mild to serious and can last from a few hours to several days. C. botulinum and some chemicals affect the nervous system, causing symptoms such as 

headache



tingling or numbness of the skin



blurred vision



weakness



dizziness



paralysis

Question no. 3. When should people with foodborne illnesses see a health care provider?

People with any of the following symptoms should see a health care provider immediately: 

signs of dehydration



prolonged vomiting that prevents keeping liquids down



diarrhea for more than 2 days in adults or for more than 24 hours in children



severe pain in the abdomen or rectum



a fever higher than 101 degrees



stools containing blood or pus



stools that are black and tarry



nervous system symptoms



signs of HUS

If a child has a foodborne illness, parents or guardians should not hesitate to call a health care provider for advice.

Question no. 4. How are foodborne illnesses treated? The only treatment needed for most foodborne illnesses is replacing lost fluids and electrolytes to prevent dehydration. Over-the-counter medications such as loperamide (Imodium) and bismuth subsalicylate (Pepto-Bismol and Kaopectate) may help stop diarrhea in adults. However, people with bloody diarrhea—a sign of bacterial or parasitic infection—should not use these medications. If diarrhea is caused by bacteria or parasites, over-the-counter medications may prolong the problem. Medications to treat diarrhea in adults can be dangerous for infants and children and should only be given with a health care provider’s guidance. If the specific cause of the foodborne illness is diagnosed, a health care provider may prescribe medications, such as antibiotics, to treat the illness. Hospitalization may be required to treat lifethreatening symptoms and complications, such as paralysis, severe dehydration, and HUS.

Question no. 5. How are foodborne illnesses prevented?

Foodborne illnesses can be prevented by properly storing, cooking, cleaning, and handling foods. 

Raw and cooked perishable foods—foods that can spoil— should be refrigerated or frozen promptly. If perishable foods

stand at room temperature for more than 2 hours, they may not be safe to eat. Refrigerators should be set at 40 degrees or lower and freezers should be set at 0 degrees. 

Foods should be cooked long enough and at a high enough temperature to kill the harmful bacteria that cause illnesses. A meat thermometer should be used to ensure foods are cooked to the appropriate internal temperature: o 145

degrees for roasts, steaks, and chops of beef, veal, pork, and lamb, followed by 3 minutes of rest time after the meat is removed from the heat source

o 160

degrees for ground beef, veal, pork, and lamb

o 165

degrees for poultry



Cold foods should be kept cold and hot foods should be kept hot.



Fruits and vegetables should be washed under running water just before eating, cutting, or cooking. A produce brush can be used under running water to clean fruits and vegetables with firm skin.



Raw meat, poultry, seafood, and their juices should be kept away from other foods.



People should wash their hands for at least 20 seconds with warm, soapy water before and after handling raw meat, poultry, fish, shellfish, produce, or eggs. People should also wash their hands after using the bathroom, changing diapers, or touching animals.



Utensils and surfaces should be washed with hot, soapy water before and after they are used to prepare food. Diluted bleach—1 teaspoon of bleach to 1 quart of hot water—can also be used to sanitize utensils and surfaces.

Part IV. Discussion ( kamo na buhat ana and sa uban ly hehehhhe sayun ra ana xa )

References:

1. Kuchenmüller T, Hird S, Stein C, Kramarz P, Nanda A, Havelaar A. Estimating the global burden of foodborne diseases--a collaborative effort. Euro Surveill. 2009;14:18. [PubMed] 2. Jones KE, Patel NG, Levy MA, Storeygard A, Balk D, Gittleman JL. Global trends in emerging infectious diseases. Nature. 2008;451:990– 93. [PMC free article] [PubMed] 3. Tan LJ. Diagnosis and management of foodborne illnesses: a primer for physicians and other healthcare professionals. MMWR Morb Mortal Wkly Rep. 2004;50:1–69. 4. Rostami K, Villanacci V. Microscopic enteritis: novel prospect in coeliac disease clinical and immuno-histogenesis. Evolution in diagnostic and treatment strategies. Dig Liver Dis. 2009;41:245– 52. [PubMed] 5. Obasanjo O. Foodborne illness primer for physicians and other healthcare professionals: a review. Medscape. Available from: http://www.medscape.com/viewarticle/726313 . Accessed at: Oct, 2010. 6. Foodborne Illness Primer Work Group. Foodborne illness primer for physicians and other health care professionals. Nutr Clin Care. 2004;7:134–40. [PubMed] 7. Harrison JW, Svec TA. The beginning of the end of the antibiotic era? Part II. Proposed solutions to antibiotic abuse. Quintessence Int. 1998;29:223–29. [PubMed]

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