Interjections At Hyper

INTERJECTIONS AT hyper/hypotonic 1 g B5 – halts post op paralytic ileus Autoimmune disease (lupus, RA) m/c cause of death CV disease – inflammation of intima of heart Definition in MG +2 = give mg malate orally ADVANTAGES: drive things into the cell EX: vit C, minerals (cancer, angina, fibro, celiac, post op IBD) Glc in a hypoglycemic coma MG salts – iv to female who go into early labour relaxes AA in the brain increases blood flow and increases oxygen supply reprofusion causes more damage than ischema Blood flow comes back and pushes all the meta waste production back into cells Gingko decreases reprofusion damage Give before ischemic event Isotonic SALINE: in humans (anything less is hypotonic anything more is hypertonic) Vit A: 5% solution of dextrose (D5W) Dosing can be done in IU’s or retinol units Needs to be in glass b/c in plastic it sticks to the sides of the wall and up to 30% stays bag SXs of def: visual problems (night blindness) insomnia fatigue and dry skin acne Toxicity can cause anemia alopecia and lv enlargement (stored) Indicated for cancer/angina/fibromyalgia Celiac disease Post op paralytic ileus, IBD, hep c, hiv, Anything with absorption or consumption problems (cachexia) VIt D: Vit E: not mixed unless compounded: synthetic D L alpha tocopherol vision sense and gate: gait and vibratory sense VIT E is beneficial for sickle cell anemia and thalasemia Vit K: K1 – bld K2 – bone K 3 – cancer (interaction with vit C - +) Can falsely increase 17-ketosteroids Cautions/Toxicity symptoms: risk of death from anaphylaxis shock

therefore in IV in emergency setting only Biotin: FAT SOLUBLE Forms injected: D5W and saline Typical dosing: 1 or 1.2 mg/.ml – compounding pharmacist can make id higher concentration deficiency can mimic a B1 deficiency Cautions and toxicity symptoms: no info on B1 – thiamine: Forms injected: IM dextrose, ringers (has K+ other electrolytes in it as well as NaCl) , lactate ringers (has sugars in it as well as NaCl), D5W, D10W, saline, sterile water If dehydrated saline is a good way to go but if low in nutrients do ringers or lactate ringers Cautions/Toxicity:; risk of allergic reaction when given IM – controversy over B1 or precursors B2 – riboflavin Forms injected: saline, sterile water Unstable in light – must be mixed and stored Cautions and toxicity: ;fairly safe B3 – Forms injected: can give IM but painful Urine glc test can be altered and urine catecholamines Monitore AST/ALT:; (if elevatede ust go back to niacin) B5 – Forms injected: IV form is dexpanterol Typical dosing: has seen patients double that Usages: use in paralytic ileus Important for cortisol production and atp production (mg+2 also) B6 – Forms injectedL sterile water saline Sensitive to light (can’t store for long period) don’t premix more than 8 hours in advance Usages: Mg+2 is a cofactor will add some to the mix Isonaizide (tx TP) and BCP block B6 Folic Acid:; Forms injected: best way to give is IM because doesn’t mix well and will clog up the line

Typical dosing: benefits at high doses (up to 20 mg/d) All mimic a b23 defc change RA: use methotrexate –bocks folic acid B12 : Forms injected: IV or IM – 2 diff preparations (different buffers) Cheap cyanocobalimine is typically used by medical doctors - 80% excreted by ki Hydrxoco: 5% excreted by KI, 5g to stop cyanide poisoning Cyanocobalamine: is CI in lebers: bilateral antral vision loss, genetic, not reversible Almost always assoc with smoking can’t meta cyanide = blind female sambucus and prunes seratona CI twice the price Methlyco: 80% absorbed increase melatonin