Imagerie Spectroscopique En Rmn
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6. Imagerie Spectroscopique en RMN Responsable Adjoint
Danielle GRAVERON-DEMILLY, IR-HC, UCB, HDR Dominique SAPPEY-MARINIER, MCU-PH, UCB-HCL, HDR Latifa FAKRI-BOUCHET, MCU IUTB François COTTON, PUPH Frédérique FOULON, IR Applications de la SRM et de l’ISRM à l’étude des principales maladies. Micro-antennes implantables Méthodes avancées de Traitement du Signal et d’acquisition pour l’ISRM ultra-rapide
Spectre H1 Cerveau de souris, 7T
Images métaboliques d’un cerveau humain neuro-infecté, quantifiées avec le logiciel jMRUI
Imageur virtuel fondé sur la Mécanique Quantique
Projet européen Marie-Curie, FAST 1
26 Septembre 2008
Advanced Signal-Processing for Ultra-Fast Magnetic Resonance Spectroscopic Imaging, and Training Marie Curie Research Network, MRTN-CT-2006-035801 Coordinator:
CONSORTIUM
Danielle Graveron-Demilly
16 9
Partners Countries: 8 EU Member States + 1 Associated Country 11 Universities 3 Industrial Partners (Philips, Siemens, Sanofi-Aventis) 2 SME 3 Experts 4 Less-Favoured Regions within EU 2
26 Septembre 2008
UCBLyon1, UoManchester, KULeuven, ULeipzig, ILSPAthens, CITChaldika, UCLouvain, UABarcelona, RUNijmegen, ISIBrno, EPFLausanne, Philips Medical Systems, Siemens Medical Solutions, Sanofi-Aventis, Alter systems
http://www.fast-mariecurie-rtn-project.eu
jMRUI
Advanced Signal Processing for Medical MRS • • •
• • • • • • •
Plug-ins http://www.mrui.uab.es/mrui Advanced DICOM for MRS/MRI/MRSI ‘Whole-Metabolite’ DataBase Generation with NMRSCOPE, for In vivo MRS and MASNMR, at arbitrary field strength. QUEST for fitting ‘whole-metabolite’ signals (generated/measured database) NonLinear LeastSquares Quantitation: AMARES Black-Box Quantitation based on Singular Value Decomposition 3D MRSI Quantitation 1D/Time series Quantitation Preprocessing: Removal of Results from a file in the new DICOM Standard Water/Macromolecule signals, etc. Error Estimation : CramérRao Lower Bounds
• Environments : • Windows 2000, XP, Vista • Linux 3
• Free for Academia • Registration on our Website • Software Support Mailing-list
jMRUI Software Package
• •
http://www.mrui.uab.es/mrui/ Environments: Windows 2000, XP, Vista, Linux Free for Academia and hospitals Licenses sold to the main pharmaceutical companies
1200 1000 jMRUI mMRUI
No of users
• •
Trend in MRUI Users
800 600 400 200 0 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Year
Users per Type of Institution
Users per geographical area
34% NORTHAMERICA 33%
Hospital / Medical Center
AFRICA ASIA
Research Institute
AUSTRALASIA
University / Med School
EUROPE NORTH-AMERICA
EUROPE 48%
56%
SOUTH-AMERICA
10%
4
26 Septembre 2008
Danielle GRAVERON-DEMILLY, IR-HC, UCB, HDR Dominique SAPPEY-MARINIER, MCU-PH, UCB-HCL, HDR Latifa FAKRI-BOUCHET, MCU IUTB François COTTON, PUPH Frédérique FOULON, IR Applications de la SRM et de l’ISRM à l’étude des principales maladies. Micro-antennes implantables Méthodes avancées de Traitement du Signal et d’acquisition pour l’ISRM ultra-rapide
Spectre H1 Cerveau de souris, 7T
Images métaboliques d’un cerveau humain neuro-infecté, quantifiées avec le logiciel jMRUI
Imageur virtuel fondé sur la Mécanique Quantique
Projet européen Marie-Curie, FAST 1
26 Septembre 2008
Advanced Signal-Processing for Ultra-Fast Magnetic Resonance Spectroscopic Imaging, and Training Marie Curie Research Network, MRTN-CT-2006-035801 Coordinator:
CONSORTIUM
Danielle Graveron-Demilly
16 9
Partners Countries: 8 EU Member States + 1 Associated Country 11 Universities 3 Industrial Partners (Philips, Siemens, Sanofi-Aventis) 2 SME 3 Experts 4 Less-Favoured Regions within EU 2
26 Septembre 2008
UCBLyon1, UoManchester, KULeuven, ULeipzig, ILSPAthens, CITChaldika, UCLouvain, UABarcelona, RUNijmegen, ISIBrno, EPFLausanne, Philips Medical Systems, Siemens Medical Solutions, Sanofi-Aventis, Alter systems
http://www.fast-mariecurie-rtn-project.eu
jMRUI
Advanced Signal Processing for Medical MRS • • •
• • • • • • •
Plug-ins http://www.mrui.uab.es/mrui Advanced DICOM for MRS/MRI/MRSI ‘Whole-Metabolite’ DataBase Generation with NMRSCOPE, for In vivo MRS and MASNMR, at arbitrary field strength. QUEST for fitting ‘whole-metabolite’ signals (generated/measured database) NonLinear LeastSquares Quantitation: AMARES Black-Box Quantitation based on Singular Value Decomposition 3D MRSI Quantitation 1D/Time series Quantitation Preprocessing: Removal of Results from a file in the new DICOM Standard Water/Macromolecule signals, etc. Error Estimation : CramérRao Lower Bounds
• Environments : • Windows 2000, XP, Vista • Linux 3
• Free for Academia • Registration on our Website • Software Support Mailing-list
jMRUI Software Package
• •
http://www.mrui.uab.es/mrui/ Environments: Windows 2000, XP, Vista, Linux Free for Academia and hospitals Licenses sold to the main pharmaceutical companies
1200 1000 jMRUI mMRUI
No of users
• •
Trend in MRUI Users
800 600 400 200 0 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Year
Users per Type of Institution
Users per geographical area
34% NORTHAMERICA 33%
Hospital / Medical Center
AFRICA ASIA
Research Institute
AUSTRALASIA
University / Med School
EUROPE NORTH-AMERICA
EUROPE 48%
56%
SOUTH-AMERICA
10%
4
26 Septembre 2008
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