Guillian Barre

Guillian barre’ Syndrome • Widespread inflammatory demyelination of peripheral and ANS • It’s ascending in nature, LMN involvement ? caused by viral infection GI, flu A→ full stomach, difficult intubation if TMJ involvement B→ respiratory involvement C→ arrhythmia, autonomic dysfunction D→ NO Sux, (↑K), ↑ sensitivity to NDMR GI→ bowel obstruction CNS → demyelination • Pre-op: PFT, ABG, CXR, ECG, CBC, Lytes • Before induction have an art-line in place, unpredictable response to intubation and induction, consider CVP, have N. stimulator in place • Post-op: continue mech vent (ICU) • In Pt with previous disease assess for residual neuropathy, and do PFT • In pregnancy→ ↑ premature labor, epidural OK, avoid Spinal → severe hypotension