Gentamicin Drug Summ

Score: _________ Grade: ___________

DRUG SUMMARY Name of Drug Generic (Brand)

Date Ordered

Classification

Gentamycin (Garamycin)

April 29, 07

Anti-infectives

Dose Mechanism Frequency of Action Route 37.5mg IVTT od ANST (-)

Inhibits protein synthesis in bacteria at level of 30S ribosome, bactericidal action.

Specific Indication

Side Effects

Treatment of serious gramnegative bacillary infections and infections caused by staphylococci when penicillins or other less toxic drugs are contraindicated

EENT: ototoxicity (vestibular and cochlear). GU: nephrotoxicity. F and E: hypomagnesemia. MS: muscle paralysis (high parenteral doses). Misc: hypersensitivity reactions.

Nursing Implications

BEFORE: ~ Assess child for infection (vital signs, wound appearance, sputum, urine, stool, WBC) at beginning of and throughout therapy. ~ Obtain specimens for culture and sensitivity before initiating therapy. First dose may be given before receiving results. ~ Monitor intake and output and daily weight to assess hydration status and renal function. ~ Assess child for signs of superinfection (fever, upper respiratory infection, vaginal itching or discharge, increasing malaise, diarrhea). DURING: ~ Advise child of the importance of drinking plenty of liquids. ~ Missed doses should be taken as soon as possible if not almost time for next dose; do not double doses. AFTER: ~ Instruct child’s mother to take as directed for full course of therapy. ~ Mother should assess skin and inform health care professional if skin irritation develops or infection worsens.

Reference:

DAVIS DRUG GUIDE FOR NURSES 8th EDITION___