Ranitidine Drug Summ

Score: _________

Grade: _____________

DRUG SUMMARY Name of Drug Generic (Brand)

Ranitidine (Zantac)

Date Ordered

Classificatio n

Dose Frequency Route

Mechanism of Action

Specific Indication

Side Effects

Nursing Implications

Antiulcer agents

50 mg q8hr IVTT

Inhibits the action of histamine at the H2receptor site located primarily in gastric parietal cells, resulting in inhibition of gastric acid secretion

Short-term treatment of active duodenal ulcers and benign gastric ulcers

CNS: confusion, dizziness, drowsiness, hallucinations, headache. CV: ARRHYTHMIAS. GI: altered taste, black tongue (ranitidine bismuth citrate only), constipation, dark stools (ranitidine bismuth citrate only), diarrhea, drug-induced hepatitis (nizatidine, cimetidine), nausea. GU: decreased sperm count, impotence. Endo: gynecomastia. Hemat: AGRANULOCYTOSIS, APLASTIC ANEMIA, anemia, neutropenia, thrombocytopenia. Local: pain at IM site. Misc: hypersensivity reactions.

BEFORE: >Assess patient for epigastric or abdominal pain and frank or occult blood in the stool, emesis, or gastric aspirate. >Assess geriatric and debilitated patients routinely for confusion. Report promptly.

In addition, ranitidine bismuth citrate has some antibacterial action against H. pylori.

Reference:

DURING: >Administer over at least 5 min. Rapid administration may cause hypotension and arrhythmias. AFTER: >Ranitidine may cause falsepositive results for urine protein; test with sulfosalicylic acid. >Administer with meals or immediately afterward and at bedtime to prolong effect.

DAVIS DRUG GUIDE FOR NURSES 8th EDITION___