Esmo Estocolmo 2008 Gastric Ca
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Adenocarcinoma de estómago y de la unión gastroesofágica
No resecado
Resecado
Óptima (D1-3)
Subóptima (< D1)
Quimioterapia pre- y post- operatoria •MAGIC Trial: Cunningham D. N Engl J Med 2006; 355: 11-20. ACCORD07-FFCD 9703 Trial: Boige V JP, ASCO 2007 Annual Meeting Proceedings Part I. J Clin Oncol 2007: 25 (Abstr 4510). OS 5 años 36-38% vs 23-24% Estudios Fase 3
Quimioterapia postoperatoria •MAGIC Trial: •ACCORD07-FFCD 9703 Trial OS 5 años 36-38% vs 23-24% No evidencia
Okines A., Cunningham D. Progress in the multidisciplinary treatment of gastrointestinal cancers, impact on clinical practice: peri-operative management of gastro-esophageal cancer. Annals of Oncology Advance Access published on September 1, 2008, DOI 10.1093/annonc/mdn440. Ann Oncol 19: vii259-vii265
Quimiorradioterapia postoperatoria
INT 0116: Macdonald JS. N Engl J Med 2001; 345: 725-730. OS 5 años 50% vs 40% Estudio Fase 3
No resecado
Resecado
Óptima (D1-3)
Subóptima (< D1)
Quimioterapia pre- y post- operatoria •MAGIC Trial: Cunningham D. N Engl J Med 2006; 355: 11-20. ACCORD07-FFCD 9703 Trial: Boige V JP, ASCO 2007 Annual Meeting Proceedings Part I. J Clin Oncol 2007: 25 (Abstr 4510). OS 5 años 36-38% vs 23-24% Estudios Fase 3
Quimioterapia postoperatoria •MAGIC Trial: •ACCORD07-FFCD 9703 Trial OS 5 años 36-38% vs 23-24% No evidencia
Okines A., Cunningham D. Progress in the multidisciplinary treatment of gastrointestinal cancers, impact on clinical practice: peri-operative management of gastro-esophageal cancer. Annals of Oncology Advance Access published on September 1, 2008, DOI 10.1093/annonc/mdn440. Ann Oncol 19: vii259-vii265
Quimiorradioterapia postoperatoria
INT 0116: Macdonald JS. N Engl J Med 2001; 345: 725-730. OS 5 años 50% vs 40% Estudio Fase 3
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