Generic Name/ Trade Name/ Form of Medication
Epoetin Beta (Recormon)
Date Ordered
Classific a-tion
Dosage And Frequen cy
Mechanism Of Action
Haematop oietic drugs
500 units subcutane ous twice a week Peak: 5-24 hrs.
Mimics effect of erythropoietin. Functions as growth factor, enhancing RBC production
Indication
Contraindication
Adverse Reaction
Treatment of anemia associated with chronic renal failure on or not on dialysis and malignancy on or not on chemotherapy
-Poorly controlled HTN -Not to be used if the indication is for increasing the yield of autologous blood if mth preceding treatment of patient suffered MI, stroke, unstable angina pectoris, or at risk of DVT,history of thromboembo lic disease.
CNS: Headache, seizures, paresthesia, fatigue, dizziness, asthenia CV: hypertension, edema, increased clotting of arteriovenous grafts EENT: Pharyngitis G.I: Nausea, vomiting, abdominal pain Metabolic: Hyperuricemia, hyperkalimia, hyperphosphate mia
Nursing Responsiblity
-Before starting therapy, evaluate patient’s iron status. Patient should receive adequate iron supplementation beginning no later than when epoetin treatment starts and continuing throughout therapy. Patient also may need vitamin B12 and folic acid -Monitor BP before therapy. Most patients with chronic renal failure have hypertension. BP may Increase, especially when
Respiratory: Cough, shortness of breath Skin : Rash, infection site reactions, urticaria Other: pyrexia
hematocrit increases in the early part of therapy -institute diet restrictions or drug therapy to control BP -monitor hemoglobin level twice weekly until it stabilizes in the target range (10 to 12 g/dl for most patients) and maintenance dose is established, then continue to monitor at regular intervals. Resume twice weekly testing following any dosage adjustments -reduce dosage in patients who have an increase in hemoglobin level of more than 1 g/dl in any 2 week period -monitor blood counts; elevated hematocrit may cause excessive clotting -patient may
need additional heparin to prevent clotting treatments -evaluate patient who experiences a lack or loss of effect for pure red cell aplasia Patient teaching -inform patient that pain or discomfort in limbs (long bones) and pelvis, and coldness and sweating may occur after injection (usually within 2 hours) symptoms may last for 12 hours and then disappear -advise patient to avoid driving or operating heavy machinery at start of therapy. There may be a relationship between too rapid increase hematocrit and seizures -Tell patient to monitor BP at home and adhere
dietary restrictions
Nursing Problem: Injury risk for (loss of vascular access)
Assessm ent
Diagno sis
Inference
Not applicable; presence of signs and symptoms establishes an actual diagnosis of the shunt
Injury risk for (loss of vascular access) related to clotting
Loss of vascular access is inability to administer therapy or obtaining blood for testing in the vascular system Reference: http://medicaldictionary.thefreedi ctionary.com/vascul ar+access
Planning After 4 hours of duty patient will be able to maintain patent vascular access
Intervention Independent Evaluate reports of pain, numbness/tingling ; note extremity swelling distal to access Avoid trauma to shunt: e.g handle tubing gently, maintain cannula alignment. Limit activity of extremity. Avoid taking BP or drawing blood supplies in shunt extremity. Instruct patient not to sleep on side with shunt or carry packages, books, purse of the
Rational Evaluatio e n May indicate blood supply
Decreases the risk of clotting / disconnecti on
Goal met Patient is able to maintain patent vascular access.
affected extremity Collaborative: Administer medication as indicated, e.g: Heparin (low dose)
Infused on arterial side of filter to prevent clotting in the filter without systemic side effects