Drug Omeprazole

  • May 2020
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NURS 1556 Clinical Medications Worksheets (You will need to make additional copies of these forms) Generic Name Omeprazole

Trade Name Prilosec

Classification Antiulcer agents Proton pump inhibitors

Dose

Route

Time/frequency

20 mg

PO

Every day

Peak

Onset

Duration

For IV meds, compatibility with IV drips and /or solutions

30 minutes

rapid

24 hours

N/A

Mechanism of action and indications (Why med ordered)

Nursing Implications (what to focus on) Contraindications/warnings/interactions

GERD/maintenance of healing in erosive esophagitis. Duodenal ulcers. Short term treatment of active benign gastric ulcer. Pathologic hypersecretory conditions, including Zolinger-Ellison syndrome. Reduction of risk of GI bleeding in critically ill patients. Binds to an enzyme on gastric parietal cells in the presence of acidic gastric pH, preventing the final transport of hydrogen ions into the gastric lumen.

Hypersensitivity, metabolic alkalosis and hypocalcemia. Geriatrics: increased risk of hip fractures in patients using high-doses for greater than a year, Bartter’s syndrome, hypokalemia and respiratory alkalosis.

Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically)

Lab value alterations caused by medicine

Increase effects of digoxin

Common side effects Abdominal pain, nausea, vomiting, dizziness, drowsiness, fatigue, headache, weakness, constipation, diarrhea, flatulence, itching, rash, allergic reactions.

Monitor CBC with differential periodically during therapy, may cause increase AST, ALT, alkaline phosphatase and bilirubin. May cause increase serum gastrin concentrations first few weeks.

Be sure to teach the patient the following about this medication Take as directed, may cause dizziness-avoid alert activities, consult professional before taking Rx, OTC or herbal, avoid alcohol, NSAIDs, report onset of black, tarry stools, abdominal pain, persistant headache.

Nursing Process- Assessment (Pre-administration assessment) Assess for epigastric or abdominal pain and occult blood in stool, emesis, or gastric aspirate.

Assessment Why would you hold or not give this med? If blood in stool or emesis or because of allergies.

Evaluation Check after giving Assess for epigastric or abdominal pain and occult blood in stool, emesis, or gastric aspirate. Decreased abdominal pain or prevention of GI bleeding or irritation. Decreased symptoms of GERDs

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