Drug Omeprazole

  • June 2020
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NURS 1556 Clinical Medication Worksheet Karen Nielsen Generic Name Omeprazole Peak Within 2 hr

Trade Name

Classification Dose Route Time/frequency Antiulcer agent proton - pump 20 mg Po QD Prilosec inhibitor Onset Duration For IV meds, compatibility with IV drips and /or solutions N/A Within 1 hr 72-96 hr

Mechanism of action and indications: (Why med ordered) Reduces gastric acid secretion by irreversibly inhibiting the enzyme that produces gastric acid. For GERD.

Interactions with other patient drugs, OTC or herbal medicines: (ask patient specifically)

Nursing Implications (what to focus on): Contraindications/warnings/interactions Watch for metabolic alkalosis. Rx can increase risk for pneumonia due to decreased gastric pH, which promotes bacteria colonization of stomach and respiratory tract. May interact with phenytoin, Common side effects: CNS-dizziness, drowsiness, fatigue, H/A, weakness. CV-chest pain GI- abdominal pain, acid regurgitation, constipation, diarrhea, flatulence, N/V. Derm- itching, rash

Lab value alterations caused by medicine: May increase AST, ALT, alkaline phosphatase, bilirubin. Monitor CBC with diff periodically during tx. On Dilantin (phenytoin) for Tic disorder. Serum gastrin levels may rise during first 1-2 weeks. Be sure to teach the patient the following about this Omeprazole may increase the effects of phenytoin. medication: Should take once daily before eating. Avoid alcohol, NSAIDs, and foods that may increase GI irritation. Capsules should be swallowed whole. May be opened and sprinkled on cool applesauce, entire mixture ingested immediately and followed with a drink of water Nursing Process- Assessment Assessment Evaluation (Pre-administration assessment) Why would you hold or not give Check after giving this med? Assess for epigastric or abdominal pain If pt reports or exhibits signs of Decrease in symptoms of and frank or occult blood in the stool, or severe abdominal or epigastric pain, GERD. emesis. has frank or occult blood in stool or emesis.

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