Dna Replication By Parth Saha

Semiconservative Replication Messelson and Stahl (1958)

Semidiscontinuous DNA replication Reizi Okazaki (1968)

θ mode of DNA replication John Cairns (1963)

Bidirectional Movement of Replication Fork Elizabeth Gyurasits and RB Wake (1973)

RNA Primers Tuneko Okazaki (1985)

5’ ends of RNAs are labeled with Guanylyl Transferase and [α-32P]GTP Lanes a-d, before DNase treatment Lanes e-h, after DNase treatment Lanes a & e, -RNase H Lanse b & f, -exonuclease of DNA PolI Lanes c & g, -RNase H and -exonuclease of DNA PolI Lanes d & h, Wild type

Two types of E. coli replication mutants Jacob et al. (1968)

Helicase assay

DnaB Helicase Assay Lebowitz and McMacken (1986)

Cycling of β-Complex

Clamp unloading activity of Pol III* O’Donnell, 1994

Clamp unloading activity of γ-complex, O’Donnell, 1996

Interaction of β-clamp with core Pol III complex and γ-complex O’Donnell, 1996

Preferential binding of β-clamp to core in presence of primed template O’Donnell, 1996

Lagging strand replication

Initiation in E. coli OriC

Termination in E. coli

Model of decatenation