Celebrex

Brand Name: Celebrex Generic Name: Celecoxib Indications: Acute or chronic use in the treatment of the sings and symptoms of osteoarthritis and RA. Management and treatment of post-surgical or dental pain, acute pain and primary dysmenorrhea. Drug Classification: Antirheumatic, Anti-inflammatory Analgesic Mechanism of Action: Thought to inhibit prostaglandin synthesis, impeding cyclooxygenase-2 to produce anti-inflammatory, analgesic, and anti-pyretic effects. Dosage: Oseoarthritis Adult 200mg as a single dose or a 2 divided doses. RA 100-200 mg bid. post-surgical or dental pain, acute flare pain of osteoarthritis 200mg od or bid. Special Precaution: Asthma, urticaria or acute rhinitis. Children <18y/o, pregnancy, lactation, severe hepatic impairment. Pregnancy Risk: C, D in 3rd trimester Adverse Reaction: GI complaints, dizziness, bronchitis, coughing, pharyngitis, rhinitis, sinusitis, upper resp tract infection, headache, accidental injury, flu-like symptoms, peripheral edema.

Contraindications: Hypersensitivity to drugs, severe hepatic impairment, 3rd trimester of pregnancy. Form: Capsules 200 and 300mg Nursing Responsibilities:  Tell patient to report history of allergic reactions to sulfonamides, aspirin, NSAID’s.  Instruct patient to report signs of GI bleeding.  Advice patient to immediately report rash, unexplaines weight gain, or swelling.  Inform patient that it may take several days before he feels consistent pain relief.