Brand Name: Cozaar Generic Name: Losartan Potassium Indications: Hypetension, Nephepatically

Brand Name: Cozaar Generic Name: Losartan Potassium Indications: Hypetension, Nephepatically in type 2 daibetic patients, to reduce risk of CVA in patients with hypertension and left ventricular hypertrophy Drug Classification: Anti-hypertensives Mechanism of Action: Inhibits vasoconstrictive and aldosterone-secreting action of angiotensin II by blocking angiotensin II receptor on the surface of vascular smooth muscle and other tissue cells. Dosage: For Hypertension: Adults- Initially 25-50mg PO daily, For Nephropahty: Adults-50mg PO od. Special Precaution: Impaired renal or hepatic function Pregnancy Risk: C; D in 2nd and 3rd trimesters Adverse Reaction: CNS-dizziness, asthenia, fatigue, headache, insomia. CV-edema, chest pain. EENT-nasal congestion, sinusitis, pharyngitis, sinus disorder. GI-Abdominal pain, nausea, diarrhea, dyspepsia. Musculoskeletal-muscle cramps, myalgia, back or leg pain. Respiratory-cough, upper respiratory infection.

Contraindications: Patients hypersensitive to drug, breast-feeding is not recommended, causes fetal and neonatal morbidity and death when administered in the 2nd and 3rd trimester of pregnancy. Form: Tablet Nursing Responsibilities:  Monitor patients BP.  Monitor patients who are also taking diuretics for symptomatic hypotension.  Assessmpatients renal function  Tell patient to avoid salt substitutes