Brand Name: Aprovel Generic Name: Irbesartan Indications: For The Treatment
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Brand Name: Aprovel Generic Name: Irbesartan Indications: For the treatment of hypertension & treatment of renal disease in patients with hypertension and type II diabetes mellitus, as part of an antihypertensive drug regimen. Drug Classification: Antihypertensive Mechanism of Action: Inhibits the vasoconstricting and aldosterone-secreting effects of angiotensin II by selectively blocking binding of angiotensin Ii to receptor sites in many tissues. Therapeutic Effect: Lowers blood pressure. Dosage: 150 mg daily. May be increased to 300 mg or combined with other antihypertensive agents if patient is not sufficiently controlled. In hemodialyzed patients & elderly>75 yr 75 mg daily Special Precaution: Intravascular volume depletion, renovascular hypertension, renal impairment, kidney transplantation, hyperkalemia, aortic & mitral valve stenosis, obstructive hypertrophic, cardiomyopathy, ischemic cardiopathy, ischemic CV disease, primary aldosteronism & patients whose vascular tone & renal function depend predominantly on the activity of the rennin-angiotensin-aldosterone system. Pregnancy Risk Category: C (D in 2nd and 3rd trimesters)
Adverse Reaction: CNS: fatigue, anxiety, dizziness, headache., CV: chest pain, edema, tachycardia. EENT: pharyngitis, rhinitis, sinus abnormality. GI: UTI. Metabolic: hyperkalemia. Musculoskeletal: musculoskeletal trauma or pain. Respiratory: URTI. Skin: rashes. Contraindications: Pregnancy and lactation Form: Tablets: 75 mg, 150 mg, and 300 mg. Nursing Responsibilities: Monitor patient’s BP regularly. Monitor patient’s electrolytes. Assess patient’s and family’s knowledge of drug therapy. Give with a diuretic if drug is needed to control blood pressure. Place in supine position and give an IV infusion of NSS if patient becomes hypotensive. Tell patient that drug may be taken once daily with or without food. Instruct client to avoid driving and hazardous activities until CNS effects of drug are known.
Adverse Reaction: CNS: fatigue, anxiety, dizziness, headache., CV: chest pain, edema, tachycardia. EENT: pharyngitis, rhinitis, sinus abnormality. GI: UTI. Metabolic: hyperkalemia. Musculoskeletal: musculoskeletal trauma or pain. Respiratory: URTI. Skin: rashes. Contraindications: Pregnancy and lactation Form: Tablets: 75 mg, 150 mg, and 300 mg. Nursing Responsibilities: Monitor patient’s BP regularly. Monitor patient’s electrolytes. Assess patient’s and family’s knowledge of drug therapy. Give with a diuretic if drug is needed to control blood pressure. Place in supine position and give an IV infusion of NSS if patient becomes hypotensive. Tell patient that drug may be taken once daily with or without food. Instruct client to avoid driving and hazardous activities until CNS effects of drug are known.
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