Bioprofiler: Microorganism Identification By Maldi-tof Ms

Easy operation

BioProfiler - Microorganism Identification based on MALDI-TOF Mass Spectrometry Biological hazardous threats

comparing their individual peak lists to the available database.

Worldwide there is an evident danger for the use of biological hazardous agents as weapons of mass destruction. The terrifying fact about bio hazards is the possibility of its fast and uncontrollable spread into the environment.

Based on a flexible database approach the data obtained by MALDI-TOF mass spectrometry from cultivated bacterial colonies can be easily analysed.

Therefore the reliable and fast identification of microorganisms is a challenging task in mobile or stationary labs.

Identification of unknown microorganisms BioProfiler microorganism identification based on MALDI-TOF mass spectrometry is a software tool that allows the reliable identification of unknown microorganisms from their protein fingerprint in the MALDI-TOF mass spectrum by

The BioProfiler software offers two levels of operation. Easy and fast identification incorporates loading the library and starting the pattern matching based evaluation procedure. It incorporated the measurement of several substances in one go.

Key features Ready-to-use databases are available including a database for bacteria based Biological Warfare Agents ( BWA) Adjustable to new threats by creating your own database Training mode to extend existing databases or those provided by Bruker Daltonics User and application training Scoring factors allowing the interpretation of identification results

Even different microbial strains of the same species can be distinguished with the described method. The advanced level enables the laboratory professional to create an individual data base out of their own collected available samples in order to address new threats.

BioProfiler software 1 Microbial sample list 2

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2 Matching of the test substance peak against the library main spectrum 3 Microbial strain data base 4 Ranking list of identified results

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Übersicht der Bruker-Geräte?

Peptide Mass Fingerprint

Fields of application Post event identification of pathogenic microorganisms in laboratories Microbiology Research analysis Screening of microorganisms at veterinary microbiology Evaluation of harmful pathogens at mobile laboratories

Technical specifications System requirements Works on Windows XP based computers with at least 2 GHz, 512 MB RAM and 256 MB free disk capacity

Samples Bacteria (gram+/gram-), yeasts, fungi, spores

Bruker Daltonics

Instrumentation Bruker flex series mass spectrometers with instrument control software

For research use only. Not for use in diagnostic purposes.

BioProfiler

Bruker Daltonik GmbH

Bruker Daltonics Ltd

Bruker Daltonics Inc.

Leipzig · Germany Phone +49 (341)2431-30 Fax +49 (341)2431-404 [email protected] www.cbrn-bdal.de

Coventry · United Kingdom Phone +44 (2476) 855-200 Fax +44 (2476) 465-317 [email protected] www.cbrn-bdal.com

Billerica, MA · USA Phone +1 (978) 663-3660 Fax +1 (978) 667-5993 [email protected] www.cbrn-bdal.com

© BDAL 02-2007, CBRN 21/1

Reliable & Fast Microorganism Identification

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CBRN