Brand Name: Apo- Metoprolol, Betaloc, Lopressor, Novometropol Generic Name: Metoprolol Indications: PO: used alone or in combination with other agents in the treatment of Hypertension and Angina Pectoris PO, IV: Prevention of Myocardial Infarction. Unlabeled Uses: Prophylaxis and Treatment of Arrhythmias Treatment of Hypertonic Cardiomyopathy Mitral Valve Prolapse Tremors Symptomatic Treatment of Pheochromocytoma Prevention of Vascular Headache Management of Aggressive Behavior Drug Classification: Antihypertensive – Beta-adrenergic blocker, Antianginal, Betaadrenergic blocker - selective Mechanism of Action: Blocks stimulation of Beta1 adrenergic receptors with less effect on Beta2 receptor sites
Dosage: Chronic treatment of hypertension, Angina; Myocardial Infarction Prophylaxis: PO (Adults): 100-450 mg/day – single dose or bid. Myocardial Infarction Prophylaxis – Acute Treatment IV (Adults): 5mg q 2 min for 3 doses. Special Precaution: Pregnancy; Hyperthyroidism; Diabetes Mellitus; Lactation or Children Pregnancy Risk Category: B Adverse Reactions: CNS: Fatigue, Weakness, Dizziness, Depression, Memory Loss, Mental Changes, Nightmares EENT: Blurred Vision Resp: Bronchospasm, Wheezing CV: Bradycardia, Congestive Heart Failure, Pulmonary Edema, Peripheral Vasoconstriction GI: Constipation, Diarrhea, Nausea GU: Impotence, Diminished Libido Endo: Hyperglycemia, Hypoglycemia Contraindications: Uncompensated Congestive Heart Failure; Pulmonary Edema; Cardiogenic Shock; Bradycardia or Heart Block
(continuation Apo- Metoprolol, Betaloc, Lopressor, Novometropol) Form: Tab 10mg x 100’s; 50mg x 100’s; 500’s Nursing Responsibilities: General Info: monitor intake and output ratios and daily weight. Assess patient routinely for evidence of fluid overload Hypertension: Monitor blood pressure and pulse frequently during period of adjustment and periodically throughout therapy. Confer with physician prior to giving drug if pulse is <50 bpm. Vital signs and ECG should be monitored every 5-15mins during and for several hrs after parental administration. Angina: Assess frequency and duration of episodes of chest pain throughout therapy. Lab Test Considerations: May occasionally cause elevations in Potassium, Uric Acid, Lipoprotein Levels, and BUN. Hepatic and renal function and CBC should be monitored periodically in patients receiving prolonged therapy.