Basic Drug Computation Part 3

Basic Computation/s Part 3 Syrup, Suspension, Tablet, Capsule based on weight mg/kg/day or dose

Common Drugs: Antibiotics 1. Amoxicillin 50- 100 mg/kg/day Preparations: 100mg/ml 125mg/5ml 250mg/5ml 250mg/cap 500mg/cap

Antibiotics 2. Ampicillin 50-100mg/kg/day 200-400mg/kg/day – meningitis

3. Cloxacillin 50-mg/kg/day

4. Erythromycin 50mg/kg/day

Antibiotics 5. Gentamycin 5-8mg/kg/day

6. Amikacin 15mg/kg/day loading dose 10 mg/kg/day maintenance

Antibiotics 7. Chloramphenicols 50-100 mg/kg/day

8. Trimethoprim-Sulfaethoxazole 5-8 mg/kg/day

9. Cefalexin 25-50mg/kg/day

Antibiotics 10. Cefaclor 20-40mg/kg/day

11. Cefuroxime 50-100mg/kg/day 20-30mg/kg/day – oral

12. Ceftriazone 50-100mg/kg/day

Antibiotics 13. Tetracyclines 25-50mg/kg/day

Amoebicides 1. Metronidazole 30-50mg/kg/day

Antihelmintics 1. Mebendazole (Antiox) 200mg/day for 3 days

2. Pyrantel pamoate 11 mg/kg/day for 3 days

Anti-Tuberculosis 1. Ethambutol 15mg/kg/day

2. Isoniazid 10-20mg/kg/day

3. Rifampicin 10-20 mg/kg/day

4. Pyrazinamide 30-35 mg/kg/day

5. Streptomycin - 10 mg/kg/day

Other drugs 1. Paracetamol 10-15mg/kg/dose

2. Diphenhydramine 3-5 mg/kg/day

3. Mefenamic acid 6.5mg/kg/dose

Form:ula For Syrup & Susp. Weight in kgs. x mg/kg/dose x prep = ml /dose

Weight in kgs. X mg/kg/day x prep = ml/day divided by the no. of times to be given

For Tablet and Capsule: Weight divided by prep. Then compare to the desired range of the drug’s mg/kg/day or per dose