Basal Ganglia

Basal Gangl

Joshua C. Brumberg, Ph Queens College, CU [email protected]

Basal Ganglia

Basal Ganglia: Coronal

Basal Ganglia: Coronal

Basal Ganglia: Horizontal

Basal Ganglia: Horizontal

Basal Ganglia: Sagital

Basal Ganglia: Volumetric Appreciation

Basal Ganglia Loops

Basal Ganglia - Maps

Motor Loop

Cortical Input to Striatum

Medium Spiny Neurons

Inputs Onto a Medium Spiny Neuron

s onto Medium Spiny Neurons Segre

Synaptic Circuitry of the Motor Loo

Substantia Nigra

Substantia Nigra: Output

Striatal Input

Functional Organization Within Basal Ganglia

Motor vs. Associative Loops Distinc

Modality Specific Interactions

ecificity of Within sal Ganglia Connections

Differential Inputs to GPi

GPi Outputs

GPi  VA/VL Thalamus

GPi  VA/VL Thalamus

Targeting a Neuron in GPi

and Out of the ubthalamic Nucleus

erent Pathways Distinct Neurotransmitte

Globus Pallidus: Outputs

Gpe Outputs

Basal Ganglia Connections a Sagittal View

The Basal Ganglia

Chemically Segregated Outputs

Striatal Pathway at Work

Timing of Activity

Direct vs. Indirect Chemistry

To be Indirect Or Direct?

Parkinson’s Disease

ng Strength of Connections Within Motor Path

Parkinson’s Disease Patholog

Huntington’s Disease

direct vs. Direct inical Relevance eviewed

Direct vs. Indirect

Blood Supply

Globus Pallidusi Lesion

Substantia Nigra Lesion

Basal Ganglia a Review

LOOPS

Loops

The End