Anti Psychotic Drugs
This document was uploaded by user and they confirmed that they have the permission to share it. If you are author or own the copyright of this book, please report to us by using this DMCA report form. Report DMCA
Overview
Download & View Anti Psychotic Drugs as PDF for free.
More details
- Words: 361
- Pages: 10
Ant i Psy ch ot ic Dru gs Psychology 2800
09/08/09
Psychology 2800
1
In tr oduct io n
Called that for a good reason Diminish the symptoms of schizophrenia
Negative symptoms Catatonia withdrawal
Positive symptoms Delusions Paranoia
09/08/09
Psychology 2800
2
In tr oduct io n
Neruoleptic is another term
‘clasping the neuron’
Also used to be called ‘Major Tranquillizers’ As compared to B & B Not really an appropriate name, though they do have tranquillizing effects.
09/08/09
Psychology 2800
3
In tr oduct io n
Most useful classification is typical vs. atypical antipsychotics
Typical • Chloropromazine • Promazine • haliparidol
Atypical • Best known is clozapine
09/08/09
Psychology 2800
4
In tr oduct io n
09/08/09
Laborit tried antihistamines and the rest is history Administered orally or by depot injection Crosses barriers Absorbed very slowly Completely broken down by metabolism Psychology 2800
5
Ho w d o t hey wo rk?
Block DA receptors D2 especially Direct relationship between effectiveness and D2 binding (r =1.00) Also blocks Ach, 5Ht and H Alters GABA, peptides Blocks NE receptors, causes an increase in NE synthesis
09/08/09
Psychology 2800
6
09/08/09
Psychology 2800
7
Ho w d o t hey wo rk?
Key brain regions:
Mesolimbic dopamine system That’s
the reward system
nigrostriatal Could
be the atypicals have less effect in this area (more DA here) Drugs that block cholinergic receptors stop Parkinsonian symptoms, so do atypicals. 09/08/09
Psychology 2800
8
Sid e E ff ec ts
Parkinson’s symptoms are the nastiest side effect
Thermoregulation problems Seizures Liver failure
09/08/09
Important to get the right drug in the right does
Exceedingly rare, but happens with atypicals Psychology 2800
9
Sid e E ff ec ts Probably only in middle eastern/Mediterranean folks Basically slows all animals down, us included Dissociative effects Reduces sex drive No withdrawal to speak of No street value at all.
09/08/09
Psychology 2800
10
09/08/09
Psychology 2800
1
In tr oduct io n
Called that for a good reason Diminish the symptoms of schizophrenia
Negative symptoms Catatonia withdrawal
Positive symptoms Delusions Paranoia
09/08/09
Psychology 2800
2
In tr oduct io n
Neruoleptic is another term
‘clasping the neuron’
Also used to be called ‘Major Tranquillizers’ As compared to B & B Not really an appropriate name, though they do have tranquillizing effects.
09/08/09
Psychology 2800
3
In tr oduct io n
Most useful classification is typical vs. atypical antipsychotics
Typical • Chloropromazine • Promazine • haliparidol
Atypical • Best known is clozapine
09/08/09
Psychology 2800
4
In tr oduct io n
09/08/09
Laborit tried antihistamines and the rest is history Administered orally or by depot injection Crosses barriers Absorbed very slowly Completely broken down by metabolism Psychology 2800
5
Ho w d o t hey wo rk?
Block DA receptors D2 especially Direct relationship between effectiveness and D2 binding (r =1.00) Also blocks Ach, 5Ht and H Alters GABA, peptides Blocks NE receptors, causes an increase in NE synthesis
09/08/09
Psychology 2800
6
09/08/09
Psychology 2800
7
Ho w d o t hey wo rk?
Key brain regions:
Mesolimbic dopamine system That’s
the reward system
nigrostriatal Could
be the atypicals have less effect in this area (more DA here) Drugs that block cholinergic receptors stop Parkinsonian symptoms, so do atypicals. 09/08/09
Psychology 2800
8
Sid e E ff ec ts
Parkinson’s symptoms are the nastiest side effect
Thermoregulation problems Seizures Liver failure
09/08/09
Important to get the right drug in the right does
Exceedingly rare, but happens with atypicals Psychology 2800
9
Sid e E ff ec ts Probably only in middle eastern/Mediterranean folks Basically slows all animals down, us included Dissociative effects Reduces sex drive No withdrawal to speak of No street value at all.
09/08/09
Psychology 2800
10
Related Documents
Anti Psychotic Drugs
May 2020 10
Anti Psychotic Drugs List
June 2020 8
Anti Psychotic Drugs
April 2020 25
Anti Fungal Drugs
April 2020 26
Anti Tb Drugs
December 2019 29More Documents from "dhainey"