Algoritma Terapi Hipertensi Dengan Ckd.docx

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TUGAS PEKRKULIAHAN INTENSIF FARMAKOTERAPI 2 HIPERTENSI DENGAN GAGAL GINJAL

DI SUSUN OLEH: MASRUIYATUL INAYAH (164820144900027) RASTINAH (164820145000037) VERA CANDRA C.P (164820145080045) VINA VALENTINA (164820145090046)

SI FARMASI UNIVERSITAS HARAPAN BANGSA PURWOKERTO 2019

Algoritma Terapi Hipertensi dengan CKD Pengobatan Hipertensi pada Pasien dengan CKD

Sasaran BP <130/80 mm Hg (Kelas I)

Albuminuria (≥ 300 mg/d or ≥300 mg/g creatinine)

Yes

No

ACE Inhibitor

Usual “first line”

(kelas 2a)

medication choices

ACE Inhibitor Intolerant

Yes

No

ARB

ACE inhibitor

(kelas 2b)

(kelas 2a)

FUNGSI OBAT: ACE-I (ANGIOSTENSIN CONVERTING ENZYM INHIBITOR) : Memblok angiostensin converting enzym sehingga angiostensin II tidak terbentuk sehingga tidak terjadi vasokonstriksi sehingga tekanan darah menurun. Contoh: Captropril, Isinopril ARB :Dengan reseptor angiostensin 1 di pembuluh darah ,hal ini dapat mengurangi efek fisiologi angiontensin ( Jurnal : Destiani p Dika , Dkk). Contoh: Valsartan, Ibersartan

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