(7) Kuliah Cushing-converted.pdf

  • December 2019
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CUSHING DISEASE; PANDUAN KLINIS DIAGNOSIS & TATA LAKSANA Oleh;

Eva Niamuzisilawati,dr.SpPD

DIVISI ENDOKRINOLOGI METABOLIK DIABETES FK UNS/RSUD Dr Moewardi 2018

Gambaran HPA Axis pada individu sehat dan Cushing disesase

Normal HPA Physiology

Physical Features

Treatment ◼ ◼ ◼

Stop exogenous glucocorticoid Surgery Medication to control hypercortisolism ◼



◼ ◼

Mitotane, ketoconazole, metyrapone, aminoglutethimide, trilostane, and etomidate Often fail

Radiation if surgery not possible Must have stress-dose steroids pre-, intra-, post-op

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