EXECUTIVE SUMMARY April 2009
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Capitalizing on New Opportunities for Stem Cell Products
Overview
REPORT #09-002
Report Objectives • Identify new/expanding stem cell research opportunities as a result of the ban on federal funding for research on human embryonic stem cells being lifted • Estimate market share for stem cell research products • Project growth of stem cell research products by market segment and geographic region • Learn types and species of stem cells scientists intend to use • Determine level of satisfaction with stem cell media and unmet needs with respect to stem cell products and cell lines • Uncover interest in integrated stem cell workflow products and services
This analysis also provides suppliers with critical insight into optimizing product offerings based upon scientists’ level of satisfaction with stem cell culture products and the level of interest in developing integrated stem cell product lines and services. The scientists surveyed share their opinions on what new product/technologies would be most beneficial to their research. Additionally, the report reveals what channels stem cell scientists use to access information relevant to their research, which in turn can be used by suppliers to more effectively target their products and services. The March 2009 policy change could have major implications for life science suppliers as academic scientists consider conducting research on previously unavailable embryonic stem cell lines. While the excitement about embryonic stem cell research is on the rise, including in the pharmaceutical and biotech industry, suppliers need actionable information about scientists’ plans to pursue research using all types of cell lines in a global market. This report provides insights into the origins and sources of stem cells currently used in the lab (adult, embryonic, induced and pluripotent) and those likely to be used over the next several years—in addition to differentiated cell types and associated diseases under investigation—allowing suppliers to anticipate the types of stem cell culture products scientists will need to purchase. Moreover, this report includes a supplemental section about scientists who plan to conduct stem cell research in the near future to help companies better anticipate the stem cell product needs of new customers. Capitalizing on New Opportunities for Stem Cell Products provides a roadmap for stem cell product suppliers to help navigate a landscape that is poised for change—and growth. This analysis was designed to guide suppliers in redirecting resources to new areas and markets, and to help refine current offerings by making them more responsive to scientists who are already engaged in stem cell research.
hoose C y h W eport? This R age 4) (see p
Capitalizing on New Opportunities for Stem Cell Products ©2009 BioInformatics, LLC
BioInformatics market insights from gene to drug 2111 Wilson Blvd Suite 250 Arlington, VA 22201 www.gene2drug.com 703.778.3081 (fax) Executive Summary Page 1 of 6
Analyst Expertise
In Capitalizing on New Opportunities for Stem Cell Products, we surveyed close to 500 scientists from around the world about their current—and planned—areas of research, usage of stem cell products and preferred suppliers. This report will help you to determine areas poised for growth (i.e., media, sera, supplements and cell lines) in the stem cell research products market, identify potential key competitors (including percentage of products purchased from each major supplier), and plan a long-term strategy to secure your leading position in this
expanding market. For tactical planning purposes, the report includes detailed market share estimates across major stem cell product categories by market segment, geographic region and top suppliers. Combined with data on scientists’ stem cell research budgets and expected changes in spending through 2011, suppliers can use this information to anticipate areas of growth and product saturation.
Company Information
As a result of the March 9, 2009 reversal of the 2001 restrictions on federal funding of human embryonic stem cell research, suppliers of stem cell related products are in need of a fast, accurate assessment of new opportunities in the stem cell products market. Additionally, given that practical stem cellbased therapies can take years to develop, suppliers would benefit from a clear understanding of the wide range of products that support basic stem cell research already in progress. Capitalizing on New Opportunities for Stem Cell Products, BioInformatics LLC’s latest report, will enable suppliers to respond quickly to a market disrupted by an Executive Order, and to gain a better understanding of how today’s stem cell products market is driven by long-term stem cell research requirements.
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Overview
Report Highlights
This pre-publication discount price is only available until May 17, 2009!
Capitalizing on New Opportunities for Stem Cell Products REPORT #09-002
• Projected growth of stem cell research products market by market segment and geographic region • Anticipated stem cell research budgets for 2009 by market segment and geographic region • Expected change in spending on stem cell products and cell lines over the next two to three years (through 2011)
• Differentiated cell types that were/are/will be the focus of stem cell research for 2008, 2009, and two to three years from now (2010 and 2011) • Diseases that are the focus of stem cell research by type of stem cell • Top scientific journals respondents rate as most critical to their stem cell research • Critical stem cell conferences Stem Cell Culture Products: Top Suppliers and Budgets
• Suppliers from whom respondents purchase stem cell culture products
Frequently Asked Questions (related to):
• Products needed to support scientists’ current stem cell research
• Percent of stem cell culture product purchases made from leading suppliers
• Cell types and disease that are/will be the focus of stem cell research
• Estimated 2008 budget for stem cell culture products
• Use of embryonic versus induced pluripotent cells for specific applications • Unmet product needs and product differentiation strategies • New product and/or service development opportunities • Best channels by which to communicate with and market to stem cell researchers
Section 2. Methodology & Demographics
• Percent of 2008 budget spent on stem cell media, sera, and supplements • Estimated 2009 budget that will be dedicated to stem cell culture products and stem cell lines • Percent of 2009 budget that will be spent on stem cell media, sera, and supplements • Expected change in expenditures on stem cell media, sera, and supplements over the next two to three years (2010 and 2011) Stem Cell Media: Usage, Product Features and Special Requirements
• Objectives
• Types of media used to grow and culture stem cells
• Questionnaire design
• Percent of media that is custom vs. off-the-shelf
• Survey population
• Estimate of stem cell culture media used per month in 2008
Section 3. Presentation of the Survey Data: Respondents Conducting Stem Cell Research Research Overview and Applications
• Estimate of stem cell culture media expected to be used per month in 2009 • Expected change in stem cell culture media usage for two to three years from now (2010 and 2011) • Importance of xeno-free and animal-free types of stem cell culture media
• Length of time conducting research • Goals of stem cell research
Report Highlights
• Estimated market share of top suppliers by stem cell research product category (i.e., media, sera, supplements, and cells)
• Impact on research of lifting US restrictions on federal funding of embryonic stem cells
Analyst Expertise
• Estimated market share for stem cell research products by market segment and geographic region
• Features of stem cells studied
• Advantages of stem cell culture media from primary supplier
• Source, type, and number of different stem cell lines used in 2008
• Satisfaction with features of stem cell culture media from primary supplier
• Source, type, and number of different stem cell lines expected to be used in 2009
• Requirements for GMP conditions for stem cell culture products
Capitalizing on New Opportunities for Stem Cell Products ©2009 BioInformatics, LLC
Executive Summary Page 2 of 6
Company Information
Market Size and Share and Market Growth Potential
• Source and type of stem cell lines plan to use two to three years from now (2010 and 2011)
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Section 1. Analysis
Overview
Report Highlights
Capitalizing on New Opportunities for Stem Cell Products REPORT #09-002 Additional Analysis by:
• General sources from which respondents acquire stem cells
• Market segment
• Percent of stem cell purchases made from major sources in 2008
• Years of experience
• Percent of stem cell purchases expected to be made from major sources in 2009
• Research focus
• Geographic region
age (see p
4
• Lab size
• Commercial suppliers and/or national bank/repositories from which respondents currently purchase stem cells
Section 4. Appendices
• Percent of stem cell purchases made from commercial suppliers and/or national bank/repositories
Appendix A. Respondents Planning to Conduct Stem Cell Research
• Estimated 2008 budget for stem cell lines • Estimated 2009 budget that will be dedicated to stem cell lines • Reasons why respondents acquire stem cells from their primary suppliers • Percent of stem cells grown on feeders and sources of feeder cells • Use of 3-D cell culture in stem cell research • Reasons for interest in 3-D cell culture for stem cell research Supporting Products, Technologies, and Services
• Techniques respondents use to identify differentiated cell types derived from stem cells • Major disadvantages of techniques used to identify differentiated cell types derived from stem cells • Primary supplier of consumable products used to perform techniques for identifying differentiated cell types derived from stem cells • Stem cell-specific kits or panels currently used and planned to use in the next 12 months • Stages of stem cell workflow processes with which respondents are involved
• Time frame that respondents plan to begin stem cell research • Sources of funding that will support future stem cell research • Anticipated annual budget for stem cell culture products and stem cell lines • Sources and types of stem cells respondents plan to use in their research
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Report Highlights
• Stem cell type
• Differentiated cell types that will be the focus of stem cell research • Diseases that will be the focus of stem cell research by cell type • Sources from which respondents plan to acquire stem cells Appendix B. Verbatim Responses to Questions
Company Information
• Expected changes in the percent of stem cell purchases expected to be made from commercial suppliers over the next two to three years (2010 and 2011)
hoose Why C port? e This R )
• Do you think your stem cell research will change due to the lifting of US restrictions on federal funding for human embryonic stem cell research by the new presidential administration? Why or why not? • Like many stem cell pioneers, Ian Wilmut, the creator of Dolly the sheep, has embraced an alternative approach. Are induced pluripotent stem cells the beginning of the end for embryonic cloning? Why or why not?
• Stage of stem cell workflow that respondents would most like a new product/technology to facilitate their research • Types of stem cell-related services that respondents would be most interested in obtaining from suppliers .
Capitalizing on New Opportunities for Stem Cell Products ©2009 BioInformatics, LLC
Executive Summary Page 3 of 6
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Stem Cells: Sources, Budgets, and Special Requirements
Overview
Report Highlights (continued)
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Capitalizing on New Opportunities for Stem Cell Products ©2009 BioInformatics, LLC
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The design and analysis of Capitalizing on New Opportunities for Stem Cell Products was spearheaded by BioInformatics LLC’s Vice President of Advisory Services Tamara Zemlo, Ph.D., MPH, who has been the lead analyst on over 80 syndicated market research reports. For this study, Dr. Zemlo consulted with multiple stem cell products vendors to optimize the relevance of this study with regards to the current stem cell research market.
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BioInformatics market insights from gene to drug
REPORT #09-002
Overview
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