Vitamin K

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Vitamin K Generic Name: Phytomen adione Brand Name: Kona-K Duophar ma (M) Sdn Bhd

Prevention and treatment of hypoprothrombi nemia caused by coumarin derivativeinduced or other druginduced vitamin K deficiency, hypoprothrombi nemia caused by malabsorption or inability to synthesize vitamin K; hemorrhagic disease of the newborn

Hemostatic

Promotes liver synthesis of clotting factors (II, VII, IX, X); however, the exact mechanism as to this stimulation is unknown. Menadiol is a water soluble form of vitamin K; phytonadione has a more rapid and prolonged effect than menadione; menadiol sodium diphosphate (K4) is half as potent as menadione (K3).

Local irritation or pain, sometimes with erythema at the injection site; there may also be tenderness

Severe anaphylactoid reactions, Diaphoresis, hypersensitivity reactions, Dyspnea, abnormal tastes, Hyperbilirubinem ia, Scleroderma-like lesions, Cyanosis, flushing, or hypotension

Patients who are neonates, allergic diathesis, hypersensitivity to phytonadione or any component of the formulation.

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Oral administration is the safest and requires the presence of bile salts for absorption It should be given by very slow IV injection, or where appropriate, with continuous infusion of NaCl 0.9% or dextrose 5% into the lower section of the infusion set Must note whether client has allergic reaction with vitamin K Must not give to pregnant women and children below 2 years old Follow your doctor's orders or the directions on the label Teach patient proper use, possible side effects/appropriate interventions, and adverse symptoms to report