Tutorial Chap 4

In The Name of Allah Most Gracious Most Merciful DEPARTMENT OF HEALTH AND MEDICAL SCIENCES DEPARTMENT OF SCIENCES CENTRE FOR FOUNDATION STUDIES INTERNATIONAL ISLAMIC UNIVERSITY MALAYSIA BIOLOGY 1 HMM/ SCM1414 Tutorial 4 (CELL DIVISION) Semester 1, 2007/2008 Answer all questions on these question papers.

Name

:

……………………………………………………

Matric. No

:

……………………………………………………

Programme

:

……………………………………………………

Group no

:

……………………………………………………

For Examiner’s Use Section A

Question

Marks

Objective

B C Total Marks

__________________________________________________ This question paper consists of 12 printed pages

SECTION A Circle the correct answer 1

Diagram 1 shows a particular phase in an onion cell mitotic division.

Diagram 1 Determine the phase shown in Diagram 1. A C

2

Metaphase Telophase

S phase G2 phase

B D

G1 phase M phase

Cdk, MPF and cyclin are the cell products which involve in the regulation of cell cycle. Which of the following condition initiates mitosis to start? A B C D

4

B D

In which phase of the cell cycle, are the chromosomes duplicated? A C

3

Prophase Anaphase

Gradual increase in cyclin concentration Gradual increase in MPF concentration Sudden decrease in MPF concentration Sudden decrease in Cdk concentration

In which phases are the checkpoints of the cell cycle control system? I

G1

II

G2

III

M

IV

S

A C

5

6

Composed of nucleosomes Contains DNA and histone Consists of 150 million nucleotides Consists of two sister chromatids joint by centromere

A C

I and II I, II and III

B D

I, II and IV II, III and IV

Which is the longest phase of the cell cycle? Interphase Cytokinesis

B D

Mitosis G2 phase

Cytokinesis in plant cells occurs by the formation of cell wall aster

B D

cell plate spindle apparatus

If a cell of one organism has eight chromosomes, how many chromosomes does the organism have in its gamete? A C

9

I, II and III I, II, III and IV

I II III IV

A C

8

B D

Which of the following statements are true regarding the chromosome structure?

A C

7

I and II I, II and IV

Two Eight

B D

Four Sixteen

In a plant cell, a centrosome functions in the formation of A C

asters kinetochores

B D

centrioles spindle apparatus

10

Which of the following describe/s sister chromatids? I II III IV A C

Each has its own kinetochore They are formed during prophase Moves to the opposite poles during telophase Each has half the amount of the original chromosome’s genetic material I only B III only III and IV D II, III and IV

SECTION B Figure 1 shows the arrangement of two pairs of homologous chromosomes in a particular stage during mitosis in a cell.

P

Figure 1

a)

Name the mitotic stage shown in this figure.

[1]

……………………………………………………………………………………………………. b)

i.

Identify P.

[1]

…………………………………………………………………………………………. ii.

What is the role of P?

[1]

………………………………………………………………………………………….. iii.

Name the protein subunits which make up P.

[1]

…………………………………………………………………………………………..

c)

In the box below, draw the chromosomes in a gamete produced by normal meiotic division of the chromosomes shown in Figure 1. ( Assume that crossing over does not occur) [2]

d)

In the box below, draw one of the pairs of homologous chromosomes as they would appear after crossing over has occurred during meiosis. [2]

SECTION C 1

Describe the life cycle of one chromosome as it proceeds through the entire cell cycle. [15]

2

a)

Describe the relative concentration of MPF, cyclins, and Cdks throughout the cell cycle. [10]

b)

Define MPF and discuss briefly its role in the cell cycle. [5]

3

Do comparison between the chromosomal behaviour in meiosis and mitosis. [15]

4

Compare and contrast the detailed meiotic stages in plant and animal cells. [15]