Tripollar Imcas Boisnic

Abstract

Evaluation of the TriPollar RF technology using an ex-vivo skin model Dr. S. Boisnic, GREDECO Research Association, Pitié Salpétrière Hospital, Paris, France Introduction: In recent years various non-invasive methods have been developed for the treatment of cellulite and aged skin. One of the most popular approaches nowadays, applies RF treatments for skin tightening, collagen renewal and cellulite improvement. Objective: The aim of this ex vivo study was to test the anti-cellulite and skin tightening effects of a TriPollar RF technology on ex-vivo human skin samples Methods: Eight (8) human skin samples were harvested from abdominoplasty surgery and maintained in special survival medium. A single TriPollar treatment was performed on the skin samples using the regular clinical protocol (skin temperature control, 10 minutes exposure at 25 watts). Skin samples were maintained for 15 days after treatment in survival conditions and treatment efficacy and safety were determined based on morphometric and biochemistry measurements in treated versus control skin samples. Results: A significant increase of glycerol released by the skin was found, indicating lipolysis. Neo Collagenesis was observed following the treatment, with statistically significant repair of altered collagen and increased collagen synthesis, in skin that was experimentally aged using UV radiation. Additional findings included vasoconstriction of the capillaries. Skin tolerance and epidermal cell viability, was found to be close to that of control skin. Conclusion: The TriPollar technology was found to be effective and safe for treatment of cellulite and aged skin. Experimental results show significant increase in fibroblasts activity and collagen remodeling. Radiofrequency selectively heats fat cells to increase metabolism and secretion of liquid fat. The expected clinical effect is skin tightening, and cellulite reduction.