Health Hazard …… Produces acute or chronic effects in exposed workers • Carcinogen - cause cancer or suspected cancer causer
• Toxic Agent - poisonous / cause acute or chronic effects
• Reproductive toxin (teratogen) - could
have harmful effect on male or female reproductive system or on developing fetus • Irritant - can cause inflammation of skin or eyes
•
Route of Entry…. For a chemical to have an effect on a worker, s/he must be exposed to it and some of it must get into his/her system • Inhalation / breathing - most common route,
gases / vapors can pass to blood, solid particles inhaled into lungs • Absorption through the skin - many solids, liquids, vapors and gases can be absorbed through the skin • Ingestion / swallowing - while not intentional, failure to wash hands, eating in contaminated lab, etc. • Injection - accidents handling glass, sharps, etc.
Signs & Symptoms …. How will you know if you have been exposed? • Dose - Amount of chemical absorbed depends upon chemical strength / concentration, exposure duration, frequency of exposure
– In general, the greater the dose, the more severe the health effects
• Acute effects - occurs rapidly following brief
exposure (e.g., acid burn) • Chronic effect - develops/recurs slowly, over long period following repeated, long-term, low-level exposure (e.g., benzidine linked to bladder cancer)
Working Safely with Chemicals • • • • •
Chemical Safety Concepts Safe Use and Storage Disposal of Chemicals Emergencies Radiation Safety
Personal Protective Equipment (PPE) • Always wear PPE: – Good lab practice • Eye protection for workers • Wear enclosed goggles or face shield over safety glasses if chance of splashing or shattering – Shoes, lab coat, long pants (gives protection from falling objects and spills/splatters) – Plastic/rubber apron for caustics/corrosives – Correct gloves for chemical – Never reach into liquids, use tongs for retrieval
(Chemical) Fume Hood
• Ventilated enclosure that protects you from being exposed to chemical fumes, gases and aerosols generated within the hood • Room air drawn into the hood is vented out the stack • Hood should always be ON during use • Lower sash to marked (< sash level >) position