Tissues and tissue types
Tissues are:
• Collections of specialized cells and cell products organized to perform a limited number of functions
Histology = study of tissues
The four tissue types are: • Epithelial • Connective • Muscular • Nervous
Epithelial tissue
Layer of cells covering exposed body surfaces inside or outside • Skin • Linings of body cavities • Linings of any body opening • Linings of internal passageways Form barriers Form glands • Secretory structures from epithelium
Characteristics of epithelium Cellularity: composed of tightly bound, arranged cells Polarity: uneven distribution of materials in cells; one side always faces an opening; one side always attached to a basement membrane to adjacent tissue Attachment: one side always attached to membrane made by epithelium (basal membrane) & connective tissue underneath Avascularity: No blood vessels in epithelium Nourished by diffusion or absorption Regeneration Surface cells replaced continually by mitotic cells below
Epithelial function 1. Provide physical protection Protect from abrasion, dehydration,… 2. From a barrier for permeability Can give selective absorption or secretion Can be regulated & modified by stimuli, I.e., changed with need 3. Provide sensations: Epithelial cells deeply innervated w. sensory nerves Detect changes in environment & relay to body 4. Produce specialized secretions Glandular epithelium may be scattered in other epithelium
Classification of Epithelium
Classified by arrangement of cells into layers • • •
simple = one cell layer thick stratified = many cell layers thick pseudostratified = single layer of cells where all cells don’t reach apical surface
nuclei at found at different levels so it looks multilayered
Classified by shape of surface cells • • • •
squamous =flat cuboidal = cube-shaped columnar = tall column transitional = shape varies with tissue stretching
Squamous
Simple squamous
In protected regions for absorption • Respiratory alveoli for gas exchange In regions to reduce friction • Linings of blood vessels & heart = endothelium • Serous membranes lining body cavities • Mesothelium = any simple squamous epithelium lining ventral body cavities
Single row of cube-shaped cells, often with microvilli. • Absorption & secretion; produces mucus. Mammary and salivary glands.
Single row of tall, narrow cells • vertically oriented, oval nuclei in basal half of cell Absorption & secretion; secretion of mucus Inner lining of GI tract
Keratinized Stratified Squamous
Multilayered epithelium covered with layer of compact, dead squamous cells packed with protein keratin Retards water loss & prevents penetration of organisms
Nonkeratinized Stratified Squamous Epithelial layer
Multilayered epithelium that lacks surface layer of dead cells forming abrasion-resistant, moist, slippery layer Found on tongue & vagina
Stratified Cuboidal Epithelium
Two or more layers of cells; surface cells square Secretes sweat; ovarian hormones & produces sperm Found ovarian follicles & seminiferous tubules
Cuboidal Epithelia
Transitional Epithelium
Transitional Epithelium
Multilayered epithelium with rounded surface cells that flatten when the tissue is stretched Stretches to allow filling of urinary tract Found in urinary tract -- urinary bladder
Muscle tissue
Specialized for contraction Three types • Skeletal • Cardiac • Smooth
Muscle Tissue
Muscle Tissue
Muscle Tissue
Connective tissue functions
Establishing a structural framework Transporting fluids and dissolved materials Protecting delicate organs Supporting, surrounding and interconnecting tissues Storing energy reserves Defending the body from microorganisms
A Classification of Connective Tissues
Connective tissues contain
Specialized cells Matrix • Composed of extracellular protein fibers and a ground substance
Connective tissue proper
Contains varied cell populations Contains various fiber types A syrupy ground substance
Fluid connective tissue
Contains a distinctive cell population Watery ground substance with dissolved proteins Two types • Blood • Lymph
Supporting connective tissues
Less diverse cell population Dense ground substance Closely packed fibers Two types • Cartilage • Bone
Connective tissue proper
Contains fibers, a viscous ground substance, and a varied cell population • Fibroblasts • Macrophage • Adipocytes • Mesenchymal cells • Melanocytes • Mast cells • Lymphocytes • Microphages
Connective tissue proper
Classified as loose or dense Loose • Embryonic mesenchyme, mucous connective tissues • Areolar tissue • Adipose tissue • Reticular tissue Dense • Dense regular CT • Dense irregular CT
The Cells and Fibers of Connective Tissue Proper
Connective Tissue in Embryos
Adipose and Reticular Tissues
Dense Connective Tissues
Dense Connective Tissues
Dense Connective Tissues
Fluid connective tissues
Distinctive collections of cells in a fluid matrix Blood • Formed elements and plasma
Red blood cells, white blood cells and platelets
• Arteries carry blood away, veins carry to the heart • Capillaries allow diffusion into the interstitial fluid
Lymph
Formed Elements of the Blood
Supporting connective tissues
Cartilage and bone support the rest of the body Cartilage • Grows via interstitial and appositional growth • Matrix is a firm gel containing chondroitin sulfate • Cells called chondrocytes • Cells found in lacunae • Perichondrium separates cartilage from surrounding tissues • Three types: hyaline, elastic and fibrocartilage
The Perichondrium and Types of Cartilage
The Perichondrium and Types of Cartilage
The Perichondrium and Types of Cartilage
Bone, or osseus tissue
Has osteocytes • Depend on diffusion through canaliculi for nutrients
Little ground substance Dense mineralized matrix Surrounded by periosteum
Bone