The Laboratory Of Pharmacokinetics, Dept. Of Pharmacy, University Of Patras,
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The Laboratory of Pharmacokinetics, Dept. of Pharmacy, University of Patras, Greece organises the
1st Workshop on Pharmacokinetic/Pharmacodynamic Modeling
“Basic PK/PD modeling concepts and the role and utility of PK/PD in drug development” December 7-8, 2009
e
ec Patras, Gre
Workshop Outline (full Programme at: www.pharmacy.upatras.gr):
• Modeling & simulation in drug discovery and development • PK principles: steady state, exposure, iv vs. extravascular dosing • PD principles: kinetics of drug action, effect compartment models, turnover delays Statistical issues in modeling: weighting, model discrimination, goodness of it, • combining results from various subjects, destructive sampling strategies and population sampling designs • PK/PD modeling using WinNonlin’s newly released version 6 • Strategies for dose selection for first-in-man studies Hands-on practical exercises: one-compartment bolus iv, PK/PD modeling using an effect compartment, • simulation of time course to select optimal dose and regimen, modeling pharmacodynamic time delays, case studies on the value of modeling and simulation
Workshop Tutors: Dr. Dan Weiner, Pharsight, USA & Dr. Gregory B. Sivolapenko, Dept. of Pharmacy, University of Patras, Greece Participation: A limited number of participants will be accepted at the workshop Registration: FREE for the successful applicants, following review by the Scientific Committee. Free registration includes: workshop material, lunches, workshop dinner, hotel accommodation and travel allowance (for non-Patras residents) Application: Please send your CV and a short cover letter to: Dr. G. B. Sivolapenko, [email protected], by November 16, 2009. Venue: Conference Centre, University of Patras Campus, Patras, Greece.
Language: English
Organising Committee: I. Adamopoulos, E. Briassoulis, P. Cordopatis, C. Flordellis, C. Gogos, H. Kalofonos, A. Papapetropoulos, G. Sivolapenko, D. Skarlos Scientific Committee: V. Anastasopoulos, G. Fountzilas, N. Karamanos, D. Kardamakis, D. Pectasides, K. Tsatalas, I. Varthalitis
i
Dr. G. B. Sivolapenko, Workshop Organiser, Tel.: +30 2610 969816, Fax.: +30 2610 996302, e-mail: [email protected]
1st Workshop on Pharmacokinetic/Pharmacodynamic Modeling
“Basic PK/PD modeling concepts and the role and utility of PK/PD in drug development” December 7-8, 2009
e
ec Patras, Gre
Workshop Outline (full Programme at: www.pharmacy.upatras.gr):
• Modeling & simulation in drug discovery and development • PK principles: steady state, exposure, iv vs. extravascular dosing • PD principles: kinetics of drug action, effect compartment models, turnover delays Statistical issues in modeling: weighting, model discrimination, goodness of it, • combining results from various subjects, destructive sampling strategies and population sampling designs • PK/PD modeling using WinNonlin’s newly released version 6 • Strategies for dose selection for first-in-man studies Hands-on practical exercises: one-compartment bolus iv, PK/PD modeling using an effect compartment, • simulation of time course to select optimal dose and regimen, modeling pharmacodynamic time delays, case studies on the value of modeling and simulation
Workshop Tutors: Dr. Dan Weiner, Pharsight, USA & Dr. Gregory B. Sivolapenko, Dept. of Pharmacy, University of Patras, Greece Participation: A limited number of participants will be accepted at the workshop Registration: FREE for the successful applicants, following review by the Scientific Committee. Free registration includes: workshop material, lunches, workshop dinner, hotel accommodation and travel allowance (for non-Patras residents) Application: Please send your CV and a short cover letter to: Dr. G. B. Sivolapenko, [email protected], by November 16, 2009. Venue: Conference Centre, University of Patras Campus, Patras, Greece.
Language: English
Organising Committee: I. Adamopoulos, E. Briassoulis, P. Cordopatis, C. Flordellis, C. Gogos, H. Kalofonos, A. Papapetropoulos, G. Sivolapenko, D. Skarlos Scientific Committee: V. Anastasopoulos, G. Fountzilas, N. Karamanos, D. Kardamakis, D. Pectasides, K. Tsatalas, I. Varthalitis
i
Dr. G. B. Sivolapenko, Workshop Organiser, Tel.: +30 2610 969816, Fax.: +30 2610 996302, e-mail: [email protected]
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