Cell Structure & Function
Dr. Sunita Bhagat JR 1st year
Cell Structure & Function
What is a cell? • Smallest unit of life that can carry out all the functions of a living thing. • Various sizes and shapes • Organism- living thing – Unicellular – multicellular
Microscope Development • 1665 – Robert Hooke named cell • 1674 – Anton von Leeuwenhoek - looked at cells in pond water and blood and published his observations
Cell Theory Developed • 1838 – Schleiden – all plants are made of cells • 1839 – Schwann – all animals are made of cells
• 1855 – Virchow – all cells come from pre-existing cells
Modern Cell Theory • Cells are the basic units of all life. • All organisms are made of one or more cells • All cells come from pre-existing cells
Microscopes • Hand lens • Compound light microscope
Examples of Cells Amoeba Proteus Plant Stem
Bacteria
Red Blood Cell
Nerve Cell
Two Types of Cells •Prokaryotic •Eukaryotic
Types of Cells • Prokaryotic – Simple cell – No membrane-bound organelles – Chromosome not contained in nucleus – Small cells – Ex - bacteria
• Eukaryotic – Complex cell – Membrane-bound organelles – Chromosomes contained in nucleus – Larger cells – Ex – all other organisms
Prokaryotic • Do not have structures surrounded by membranes • Few internal structures • One-celled organisms, Bacteria
Eukaryotic • Contain organelles surrounded by membranes • Most living organisms Plant
Animal
Animal Cell
Eukaryotic Cell
Eukaryotic Cell Plant Cell
“Typical” Animal Cell
A animal cell ENDOPLASMIC RETICULUM (ER)
Rough ER Flageliu m
Smooth ER
Nuclear envelope Nucleolu s Chromati n
NUCLEU S
Plasma membrane
Centrosom e CYTOSKELETO N Microfilament s Intermediate filaments Microtubules
Ribosome s
Microvill i Golgi apparatus
Peroxisom e Mitochondrio n
Lysosome
In animal cells but not plant cells: Lysosomes Centrioles Flagella (in some plant sperm)
“Typical” Plant Cell
• A plant cell NUCLEUS
Nuclear envelope Nucleolu s Chromati n
Centrosome
Rough endoplasmic reticulum Smooth endoplasmic reticulum
Ribosomes (small brwon dots) Central vacuole Tonoplast
Golgi apparatus
Microfilament s Intermediate filaments
CYTOSKELETO N
Microtubule s Mitochondrio n Peroxisom e Plasma membrane
Chloroplas t
Cell wall
Figure 6.9
Wall of adjacent cell
Plasmodesmat a
In plant cells but not animal cells: Chloroplasts Central vacuole and tonoplast Cell wall Plasmodesmata
Plant cells have some parts that animal cells don’t • Cell Wall • Central Vacuole • Plastids – Chloroplasts – Leukoplasts – chromoplasts
What animal cells have that plant cells don’t • Centrioles– function during cell division • Lysosomes – contain digestive enzymes
Cell Parts Organelles
Cellular Organelles – small, specialized structures in the
Surrounding the Cell
Cell Membrane • Outer membrane of cell that controls movement in and out of the cell • Double layer
Plasma Membrane The plasma membrane separates the living cell from its nonliving surroundings. This membrane: Is about 8 nm thick Surround the cell and controls traffic into and out of the cell Is selectively permeable, allowing some substances to cross more easily than others.
• Cell Membrane – Double layer of lipids (fats) that lets stuff in and out of cell
Membrane Structure The phospholipids and proteins in membranes create a unique physical environment, described by the fluid mosaic model. The membrane is a fluid structure with proteins embedded or attached to a double layer of phospholipids.
Fluid Model by Singer and Nicolson 1972 - SJ Singer and G.L Nicolson proposed the fluid mosaic model which accounted for the amphipathic characteristic of proteins.
Fluid mosaic model The membrane is a fluid structure with a “mosaic” of various proteins embedded in or attached to a double layer (bilayer) of phospholipids
Structure and Function of Organelles cell (plasma) membrane
• semi-permeable membrane which regulates the passage of substances into and out of the cell • composition: protein molecules dispersed throughout a double layer of lipid (fluid mosaic)
Factors affecting permeability of cell membrane to a particular substance: • 1. molecular size of the substance • 2. electrical charge on the atom or molecule of the substance • 3. solubility of the substance in water • 4. solubility of the substance in lipid
What determines the direction of the movement of molecules (diffusion) across the cell membrane?
• concentration of substances on each side of the membrane
Active transport requires energy. • A transport protein actively pumps a specific solute across a membrane against the solute’s concentration gradient; i.e., away from where the solute is less concentrated. Membrane proteins use ATP as their energy source for active transport.
Cell Wall • Most commonly found in plant cells & bacteria • Supports & protects cells
CELL WALL n
One of the feature of plant cells that distinguishes plants from animal cells.
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Found in prokaryotes, fungi, plants and some protists.
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Situated out of plasma membrane and not one of the component of protoplasm.
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Built by cellulose chain- where it is arranged in long fibril structure.
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Space between the fibril allows water, air and soluble molecules pass through the wall without any obstacle.
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A young plant cell first secretes relatively thin and flexible wall called primary cell wall.
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Between primary wall of adjacent cell is the middle lamella, a thin layer rich in sticky polysaccharides called pectin.
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The middle lamella glues the cells together.
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The sticky middle lamella cements the cell together.
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Plasmodesmata enables transportation in between cells.
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When the cell matures and stop growing, it strengthens its wall.
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Some plants cell do this simply by secreting hardening substance into the primary wall.
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Other cell add a secondary cell wall between the plasma membrane and the primary wall.
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The secondary wall, often deposited in several laminated layers, has a strong and durable matrix that affords the cell protection and support.
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Eg: Wood consist mainly of secondary wall
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The cytoplasm of one cell is continuous with the cytoplasm of its neighbours via plasmodesmata, channel through the walls.
Functions of the Cell Wall n
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The strong wall of the cells holds the plant to make it turgid The cell wall of plants: – Maintain the shape of the cells – Prevent excessive up take of water, mineral and ions
Cell Wall vs. Plasma Membrane
Cell Wall vs. Plasma Membrane
Cell Wall vs. Plasma Membrane
Cytoskeleton • Cell support • Anchors organelles • Transports materials • Helps cell move
Inside the Cell
Nucleus • Directs cell activities • Separated from cytoplasm by nuclear membrane • Contains genetic material - DNA
Eukaryotic Cell Organelles and Function •
Nucleus – Nickname: “The Control Center” – Function: holds the DNA – Parts: 1. Nucleolus: dark spot in the middle of the nucleus that helps make ribosomes
Nucleus • Control center of cell • Contains Chromosomes • Humans have 46 in each cell • Made of DNA - control heredity - control protein synthesis
• Surrounded by double membrane – nuclear membrane
• Cell Membrane
Nuclear Membrane • Surrounds nucleus • Made of two layers • Openings allow material to enter and leave nucleus
Nucleolus • Contains RNA to build proteins
Nucleolus • • • •
Within nucleus May be more than one Makes ribosomes Rich in RNA
Cytoplasm • Gel-like mixture • Surrounded by cell membrane • Contains hereditary material
Endoplasmic Reticulum • Moves materials around in cell • Smooth type: lacks ribosomes • Rough type (pictured): ribosomes embedded in surface
Eukaryotic Cell Organelles and Function •
Endoplasmic Reticulum (ER) – Nickname: “Roads” – Function: The internal delivery system of the cell
Endoplasmic Reticulum (ER) • Transports materials through the cytoplasm • There are two distinct regions of ER – Smooth ER, which lacks ribosomes – Rough ER, which contains ribosomes
Functions of Smooth ER 1. The Smooth ER – no ribosomes attached – Function: • • • •
Synthesizes fats or lipids Metabolizes carbohydrates Stores calcium Detoxifies poison, wastes
Functions of Rough ER 1. The Rough ER – have ribosomes attached » Rough appearance because it has ribosomes
– Function: • helps Produces proteins and membranes, that’s why it has ribosomes, which are distributed by transport vesicles • Transport proteins • Helps make membranes
Ribosomes • Each cell contains thousands • Found on ribosomes & floating throughout the cell
Ribosomes • Some are free, some are attached to endoplasmic reticulum. • Smallest organelles • Found in all cells, prokaryotic and eukaryotic
Ribosomes and Function •
Ribosomes – Function: makes proteins
Mitochondria and Function •
Mitochondria – Nickname: “The Powerhouse” – Function: Energy formation •
Breaks down food to make ATP – ATP: is the major fuel for all cell activities that require energy
Mitochondria • Produces energy through chemical reactions – breaking down fats & carbohydrates • Controls level of water and other materials in cell • Recycles and decomposes proteins, fats, and carbohydrates
Mitochondrion • Site of cellular respiration – food is broken down to release energy.
Golgi Bodies • Protein 'packaging plant' • Move materials within the cell • Move materials out of the cell
Golgi Complex and Function •
Golgi Complex – Nickname: The shippers – Function: packages, modifies, and transports materials to different location inside/outside of the cell – Appearance: stack of pancakes
Golgi Body • Packages cell secretions • Makes lysosomes – Contain digestive enzymes for breaking down food in food vacuoles and old, worn out structures – ex – sperm tail after fertilization.
Lysosome • Digestive 'plant' for proteins, fats, and carbohydrates • Transports undigested material to cell membrane for removal • Cell breaks down if lysosome explodes
Lysosomes and Function •
Lysosomes: circular, but bigger than ribosomes) – Nickname: “Clean-up Crews” – Function: to break down food into particles the rest of the cell can use and to destroy old cells
Chromosomes • In nucleus • Made of DNA • Contain instructions for traits & characteristics
Vacuoles • Membrane-bound sacs for storage, digestion, and waste removal • Contains water solution • Help plants maintain shape
Chloroplasts
Chloroplast • Usually found in plant cells • Contains green chlorophyll • Where photosynthesis takes place
Chloroplasts and Function •
Chloroplasts – Function: traps energy from the sun to produce food for the plant cell – Green in color because of chlorophyll, which is a green pigment
Structures used for Movement • Cilia
•Flagella
THE END