The Cell Basic unit of plant & animal life.
Life begins with one cell Zygote – fertilized egg Embryo – zygote divides and cells multiply
Cells
begin to differentiate – change their function Brain cells, muscle cells, hair, etc.
Fetus – Foal – Adult New
cells still being produced throughout life
RBC, bone, skin, gametes
Differentiated Cells
100’s of cell types in the body All
cells have the same genetic information Function determined by the genes inherited Certain genetic signals are translated and expressed Fulfill their role in the body
Cytogenetics
The branch of biology that deals with heredity and the cellular components, particularly chromosomes associated with inheritance Genotype
– the exact genetic makeup - full hereditary information of an organism represented by the particular set of genes it possesses. Phenotype – represents its actual physical properties, such as appearance (height, weight, hair color) and or performance
2 Main Cellular Compartments
Cytoplasm Bordered
externally by the plasma membrane (cell membrane) and internally by the nuclear envelope Area where organelles found
Mitochondria, Endoplasmic Reticulum, Golgi apparatus, etc
Nucleus Control
center of the cell – contains all the genetic information in the form of DNA
Mitochondria – energy generator
Nucleolus Nucleus
Endoplasmic Reticulum -Contains Ribosomes Protein synthesis
Genetic Inheritance
Chromosome Threadlike
part of a cell that carries hereditary information – DNA – in the form of gene
Gene Hereditary
unit consisting of a sequence of DNA that occupies a specific location on a chromosome Determines a particular characteristic in an organism
Locus (loci – pl) Specific
location of a gene on a chromosome
Allele Any
of a number of alternative forms of a gene
Homologous Chromosomes
Paired – horse = 32 pair (64 individual) 1
paternal and 1 maternal Similar in length (number of DNA units) Similar genetic information - genes Allele – variations of specific gene found at particular locus Homozygous – identical alleles Heterozygous – different alleles
How to tell chromosomes apart.
Centromere Constriction
in a chromosome that divides it into two
arms Responsible for proper segregation of each chromosome pair during cell division
Length of DNA strand Made
up of units of a base, a sugar and phosphoric
acid Four bases – (A) adenine, (G) guanine, (T) thymine or (C) cytosine Order of bases contains code for formation of proteins
64 different combinations – 20 amino acids
Centromere
Acrocentric – near one end 36
Metacentric – near middle 26
(18 pair) of the autosomes (non sex chromosomes)
(13 pair) of the autosomes
Telocentric – very close to end
Karyotype
Ex. Human chromosomes (23 pair)
Terms: Mitosis -Prometaphase -Metaphase Homologous Chromosomes Sister Chromatids two identical copies
Male sex chromosome (Y) is acrocentric Female sex chromosome (X) is submetacentric