Brand name: Solu-cortef Generic name: Hydrocortisone Indication: management of adrenocortical insufficiency, relief inflammation of corticosteroid-responsive dermatoses, adjunctive treatment of ulcerative colotis Drug classification: anti-inflammatory agent, corticosteroid, glucocorticoid mineralocorticoid Mechanism of action: decreases inflammation by suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability Dosage: Adult 100-500mg IV over a period of 30sec-10min, Children/infant: not <25mg/day Special precaution: hyperthyroidism, cirrhosis, nonspecific ulcerative colitis, hypertension, osteoporosis, thromboembolic tendencies, CHF, convulsive disorders, myasthenia gravis, thrombophlebitis, peptic ulcer, diabetes Pregnancy risk category: C Adverse reaction: CNS: insomnia, nervousness GI: increased appetite Derma: hirsutism Endo: diabetes mellitus Resp: epistaxis other: cataracts, anthralgia Contraindications: serious infections, except septic shock or tuberculosis meningitis, hypersensitivity, viral, fungal or tubercular skin lesions
Form: Aerosol 10%, cream 0.5%, injection, suspension 25mg/ml, ointment 0.5%, suppository 10mg, tablets 10mg Nursing responsibilities: Monitor any sign of anaphylactic reaction Assess client’s urine, muscle weakness and wasting, weight