Product Development Action Research On Essential Oils

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Product Development Action Research On Essential Oils

A Report Submitted To Asia Network for Sustainable Agriculture and Bioresources (ANSAB) Kathmandu, Nepal

Submitted By Khilendra Gurung Himalayan Bio Trade (P) Ltd Kathmandu, Nepal June, 2004 1

Concept Nepal is one of the richest countries in the world in terms of availability of different species of medicinal and aromatic herbs. Despite the richness, we have not been able to utilize them properly. If we go through government health documents, each of them speaks on the promotion of alternative system of medicine, but in reality it has not been developed. One of the strategies to promote this system is to produce herbal formulations using modern technique and make available in domestic and international market. Need for promotion of agro forest based products have been reiterated in many government and non government organization documents. The basic objective of this product development action research as financially supported by Asia Network for Sustainable Agriculture and Bioresources (ANSAB) coordinated Public-Private Alliance (PPA) is to manufacture essential oil based herbal products.

Prospects Due to the risk of adverse effects and possible resistance of modern medicine, the world is switching at a slow pace to the practice of herbs based medicine. The herbs based medicine does not have side effects and there is no risk of drug resistance. In Nepal some Chinese and Indian brands as over the counter medicine, based on essential oils are very popular for a long time. Suicho and Balm are the best examples among them. Millions of units used to be imported in Nepal every year. However, these days due to invasion of sub standard products in cheaper price, the quality brand has disappeared. But still the market exists. At present various herbal companies are manufacturing and marketing similar products as Sancho, Sanjivani, Bojo-mint, Sparsha, Achuk, etc. which has taken a fragment of the total Nepalese market. There is still a big gap between the demand and supply.

The pain relief product The existing products based on essential oils are mainly meant for cold and cough, stuffy nose and sore throat. Pain relief product based on essential oils are lacking in the market. Some Indian brands as Moov, Iodex and the Himalayan cream are available in the market in semi solid form. The proposed pain relief product was designed for the relief of pains as rheumatism, sprain, gout, migraine etc.

Inclusion of raw materials Altogether eight (including liquid paraffin as a base) materials are blended to perfection for the manufacture of proposed pain relief product. The included raw materials are as follows: 2

SN 1 2 3 4 5 6 7 8

Raw Materials Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil Fir needle oil Base

Resources Gaultheria fragrantissima Cinnamomum camphora Eucalyptus camaldulensis Mentha arvensis Cymbopogon winterianus Juniperus communis Abies spectabilis Liquid paraffin

All the included essential oils possess similar therapeutic value related to rheumatism, sciatica, arthritis, muscular aches and pains, sprains, fatigue, headache, migraine and gout. They are usually non- toxic, non irritant and nonsensitizing to skin. Juniper berry oil and Fir needle oil are the new inclusion in the proposed products which are not yet used in any other similar products from Nepal. The base is used for the dilution of oils since they have are in high concentration and have more diffusive power.

Sample preparation for pain relief product During trial of pain relief product, 10 different samples each with 200gm were prepared with varying composition of essential oils. They were allowed for ageing and were packed in bottles of 15ml capacity each. The prepared samples were labeled and distributed to person with information on usage and indications for related ailments. The samples were prepared in such a way from lower concentration of essential oils towards higher concentration terminating in a pure blend of oils. The following are the lists of samples prepared for the approval of proposed pain relief product:

SN 1 2 3 4 5 6 7

Ingredients Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil Base

Sample No.: 1 Net Amount: 200gm Composition: Percentage (%) 21 19 15 12 1 0.5 q.s.

3

Remarks: The total estimated cost of essential oils is reasonable (Rs 6.44) for 15ml of product. However, it is mild in nature and takes time to show its effect after application because of high percentage of base.

SN 1 2 3 4 5 6 7

Ingredients Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil Base

Sample No.: 2 Net Amount: 200gm Composition: Percentage (%) 21.5 20 17 13 1 0.5 q.s.

Remarks: The total estimated cost of ingredients amounts Rs 6.71 for 15ml of the product. The percentage of base has been reduced to some extent. However, it is still mild in nature.

SN 1 2 3 4 5 6 7

Ingredients Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil Base

Sample No.: 3 Net Amount: 200gm Composition: Percentage (%) 27 21 19 13 1 0.5 q.s.

Remarks: The cost of ingredients amounts Rs 7.42 for the proposed 15ml of product. The sample is sorted in preference on the basis of effectiveness and aroma.

SN 1 2 3

Ingredients Wintergreen oil Camphor extract Eucalyptus oil

Sample No.: 4 Net Amount: 200gm Composition: Percentage (%) 27 23 19 4

4 5 6 7 8

Mint oil Citronella oil Juniper berry oil Fir needle oil Base

13.5 1 0.5 0.5 q.s.

Remarks: The cost of ingredients amounts Rs 7.77 for the proposed 15ml of product. Fir needle oil is the new addition to this blend. The sample is sorted in preference on the basis of effectiveness and aroma.

SN 1 2 3 4 5 6 7 8

Ingredients Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil Fir needle oil Base

Sample No.: 5 Net Amount: 200gm Composition: Percentage (%) 29 23 21 13.5 1 0.5 0.5 q.s.

Remarks: The cost of ingredients amounts Rs 8.09 for the proposed 15ml of product. The sample is listed in preference to the final product.

SN 1 2 3 4 5 6 7 8

Ingredients Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil Fir needle oil Base

Sample No.: 6 Net Amount: 200gm Composition: Percentage (%) 31 25 21 13.5 1 1 0.5 q.s.

Remarks: The cost of ingredients amounts Rs 8.46 for 15ml of product. The sample is bit concentrated and not preferable for the final selection.

5

SN 1 2 3 4 5 6 7 8

Ingredients Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil Fir needle oil Base

Sample No.: 7 Net Amount: 200gm Composition: Percentage (%) 32.5 25 23 13.5 1.5 1 0.5 q.s.

Remarks: The cost of ingredients amounts Rs 8.75 for 15ml of product. The sample is concentrated and not in preference for the final selection.

SN 1 2 3 4 5 6 7 8

Ingredients Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil Fir needle oil Base

Sample No.: 8 Net Amount: 200gm Composition: Percentage (%) 32.5 25 23 13.5 2 1.5 0.5 q.s.

Remarks: The cost of ingredients amounts Rs 8.88 for 15ml of product. The sample is concentrated and aroma of citronella dominates, hence not in preference for the final listing.

SN 1 2 3 4 5 6

Ingredients Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil

Sample No.: 9 Net Amount: 200gm Composition: Percentage (%) 32 26 23 13.5 2.5 1.5 6

7 8

Fir needle oil Base

0.5 q.s.

Remarks: The cost of ingredients amounts Rs 8.88 for 15ml of product. The sample is highly concentrated and aroma of citronella dominates, hence not in preference for the final listing.

SN 1 2 3 4 5 6 7

Ingredients Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil Fir needle oil

Sample No.: 10 Net Amount: 200gm Composition: Percentage (%) 31 27 23 13.5 3.5 1.5 0.5

Remarks: The cost of ingredients amounts Rs 8.84 for 15ml of product. The sample is pure blend of essential oils. However, it is highly concentrated and aroma of citronella dominates, hence not in preference for the final listing.

Samples test and feedback Altogether 10 samples were prepared based on the initial knowledge about the product. The prepared samples were tested by HBTL staffs, consultant for effectiveness, aroma, side effect and the expected cost. Based on the initial test, 3 preferred compositions (sample no. 3, sample no. 4 and sample no. 5) were selected. Then 10 replicas of 3 sorted samples were prepared and distributed to the potential consumer for feedback. A questionnaire was developed and feedback from the selected person (who have the similar complaints), who had used the product was received. After the individual level feedback, a focus group discussion was held with the individual, who used the product and received recommendation for further improvement.

Selection of sample after consumer's feedback According to the users’ feedback on effectiveness, aroma, mode of action, side effect, brand name etc, the sample no. 4 was selected for further improvement. After improvement, finally the final composition of the pain relief product was derived.

7

Composition: SN 1 2 3 4 5 6 7 8

Ingredients Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil Fir needle oil Base

Percentage (%) 27 23 19 13 1 0.5 0.5 q.s.

Selection of final product The product with final composition was distributed to persons with similar complaints, age group ranging between 15 - 65 years. It was found most effective in rheumatism, arthritis, sprain, migraine and headache. Aroma was sweet and mode of action was immediate. While using the product no side effect was recorded. The cost of the product is expected to be lower as compare to the other competitive products (Moov, Iodex and the Himalayan cream) in the market. Therefore, consumers can be benefited with this product in terms of price and its effectiveness. Also, it has the prospect to compete with other herbal care products based on essential oils (Sancho, Sanjivani, Bojo-mint etc), since it can be used in cold and cough and sore throat also.

Application The product can be applied for the relief of rheumatism, sciatica, arthritis, muscular aches and pains, sprains, fatigue, headache, migraine and gout.

Production process A simple production technology is required in the manufacturing process. All the ingredients as given in the composition will undergo for analysis first and blended in an order in closed vessels and made up to the volume with the base. The preparation is filtered twice and then filled in the bottles with the help of syringe and capped. Once again the finished product is analyzed.

Sources of raw materials Most of the raw materials were purchased from domestic sources, where the resources are sustainably managed by community and promoted by community based essential oil producers. However, few essential oils were purchased from local stockiest and bottles and liquid paraffin were purchased from India. Most of the essential oils (Wintergreen oil, Juniper oil and Fir needle oil) used in the product were purchased from HBTL and they are available as per requirement. 8

Remaining oils were purchased from Herbs Production and Processing Co. Ltd. and other private traders (Mahavir Shree International and Nepal Mentha Products), where these oils are stocked throughout year. HBTL can promote community based essential oil producers to manufacture those oils in a sustainable way.

Strategy of HBTL HBTL has thought a plan to bring its maiden herbal care pain relief product aiming to provide feasible medication for all. The following are some of the future strategies of HBTL regarding pain relief product.

Registration and trademark Prior to production, registration of company and manufacturing license of the product in Department of Drug Administration (DDA) is necessary following the prevailing rules and regulation of the department. Then only Department of Industry (DoI) will provide the trademark certificate to the product.

Production and market plan HBTL will carry out the feasibility study and will prepare the marketing strategies for the pain relief product. HBTL has targeted to produce 1, 20,000 bottles containing 15ml each of the product during fiscal year 2004/2005. In an average, 10,000 bottles will be manufactured and sold per month. The distribution will be carried out through responsible marketing and with the aid of other community based partner organizations throughout Nepal. The marketing strategy will be as follows: Distributor → Wholesaler → Retailer → Consumer

Requirement of raw materials The raw materials for the manufacture of 1, 20,000 bottles containing 15 ml of the product require as follows: SN Description Quantity (Kg) 1 2 3 4 5 6 7 8

Wintergreen oil Camphor extract Eucalyptus oil Mint oil Citronella oil Juniper berry oil Fir needle oil Base Total

486 414 342 234 18 9 9 288 1800 9

Packaging materials For the manufactured of 1, 20,000 bottles of the product required the following packaging materials: SN 1 2 3 4 5

Description Bottles with caps (15ml capacity) Packing box Stickers Corrugated carton (small) Corrugated carton (large)

Number 1,25,000 1,25,000 1,25,000 5,000 420

Manpower HBTL staffs will be recruited and an herb expert/pharmacist will be hired for the proposed Product.

10

Annex 1

Questionnaire 1. Personal background: a. Name: b. Age: c. Sex: a. b. c. d. e. f. g.

2. Physical complaints: Rheumatism Migraine Arthritis Sprain Neuralgia Gout Headache

a. b. c. d. e.

3. Effectiveness of product: Fair Good Excellent Not effective Don’t know

4. Aroma of product: a. Unpleasant b. Sweet c. Irritating d. No – response 5. Mode of action: a. Immediate b. After few minutes c. After half an hour d. No effect even after an hour 6. Suggestions:

11

Annex 2

Sample distribution and feedback • • •

Age group - 15 years to 65 years Total sample distributed – 140 no. Total response received - 69

• Most effective in: Rheumatism > arthritis > sprain > cold and cough • Aroma: Sweet > unpleasant > no response • Mode of action: Immediate > after few minutes > after half an hour • • • •

Suggestions: Launch in market with good packaging and in cheaper price Use of sprayer would be better Try in semi solid form

12

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