NURS 1566 Clinical Form 3: Clinical Medications Worksheets (You will need to make additional copies of these forms) Generic Name Conjugated estrogens Peak Unknown
Trade Name Premarin
Classification Estrogens, hormones
Onset Rapid
Dose 0.625 mg
Duration 24 hr
Route PO
Time/frequency Q day
Normal dosage range 0.3-1.25 mg daily or in a cycle
Why is your patient getting this medication Osteoporosis
For IV meds, compatibility with IV drips and/or solutions
Mechanism of action and indications (Why med ordered) Estrogen deficiency states, prevention of postmenopausal osteoporosis. Management of atrophic vaginitis. Estrogens promote the growth and development of female sex organs and maintenance of secondary sex characteristics in women. Restors hormonal balance in various deficiency states and treatment of hormonesensitive tumors.
Nursing Implications (what to focus on) Contraindications/warnings/interactions Thromboembolic disease, liver dysfunction. Use cautiously in long term use(4-5) years, may increase risk of MI, stroke, PE, DVT and dementia in postmenopausal women. Common side effects H/A, edema, MI, thromboembolism, htn, nausea, wt. Changes, amenorrhea, breakthrough bleeding, dysmenorrhea, gynecomastia, breast tenderness.
Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically) Grapefruit juice
Lab value alterations caused by medicine Inc in HDL and triglycerides, and dec serum LDL and total cholesterol. Increase serum glucose, Na, cortisol, prolactin, prothrombin and factor VII, VIII, IX, and X levels. Be sure to teach the patient the following about this medication Report significant wt. Discrepancies or steady wt. Gain. Admin with food to reduce nausea. No double doses. Don’t D/C abruptly.
Nursing Process- Assessment (Pre-administration assessment) BP, I & O, weekly wt.
Assessment Why would you hold or not give this med? Fluid retention (swelling of ankles and feet, wt, gain)
Evaluation Check after giving Normalization of estrogen levels in pt. with ovariectomy. Prevention of osteoporosis