Plant

What is layout?? 

Layout: the configuration of departments, work centers, and equipment, with particular emphasis on movement of work (customers or materials) through the system

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Basic Purpose?

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To control cross contamination

The first phase : • Which overall facility layout would best be able to handle maximum projected demand for 10 years into the future? • Determine the right type, quantity, and placement of equipment for the long lead time equipment items that are essentially integrated with the construction of the facility.

Phase two : • Identify the most effective staffing requirements and shift patterns. • Discover the reliability obtainable for the major equipment cells. • Determine the best material handling

Feasibility Macro process Review

Manufacturing Process

Personal Flow

Process Utility Pharma Production Utility

Support area

1.Feasibility: A]. Layout in terms of ROI. B]. Under what regulation body plant have to work. C]. Location approval. D]. What hazardous material used in plant.

2. Macro process review Review the project in macro level

3.Manufacturing process A]. What type of manufacturing process involved B]. What type of equipment used (new or existing) C]. What space is required

4.Personal flow A]. How many persons working in the area B]. Efficient use of personnel C]. Changing facility D]. Lay out of equipment

5.Pharma production facility: HVAC – QUALITY OF AIR Water Steam Compressed air (clean air) Electricity Vacuum Special gases ETP

6.Support Area Locker and change room, canteen, cafeteria , ware house

7.Flow of materials

a]. Perimeter Manufacturing b]. Circular flow c]. Straight line flow

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In this type of facility core area or central area is ware house and manufacturing and packaging area is on the peripheral area.

Advantage Disadvantage

: Space conservation : Contamination or mix ups .

Receiving of raw material , dispensing ,and Ware house on one side and qurantine , manufacturing ,bulk stock & packaging in central corridor . Advantage : Eliminate much of crossover trafic

 Advantage

:Minimize contamination  Disadvantage

Additional space required

Receiving Area QC PACKAGING

Dispensing Weighing Washing

Sampling And Weighing

Quarantine Capsule and Formation Coating Rooms

coriidor

Tablet formation unit Common Change Dry Syrup room Formation

corridor

Ware house corridor

Shipping room

QA

Corridor

Canteen FEMALE CHANGE ROOM

MALE CHANGE ROOM

Administration

Tablet Coating unit

Production Plant

Staff

Change Room

Toilets

Staff

Wood free zone

RAW MAT. RECEIPT

PACK. MAT. RECEIPT DISPENSARY PACK. MAT STORE

MANUFACTURING

GMP ZONE

PRIMARY PACKING

PRIMARY PACK MAT. CLEAN DOWN

SECONDARY PACKING DISPATCH

Recieveing

Quaratine (first storage)

Final storage

Package component dispensing

Raw material (Dispensing)

Granulation

Compression

Bulk Quarantine

Packaging

Shipping

Bulk stock

Thank you !!