Compound
pKa
Compound
pKa
H I
–10
O R C O H
2 to 5
H
pKa
O
H
15.7
5.2
R
H
16 to 18
6.4
O R C H
~ 17
7.0
O H R C N H
~ 17
H
O R
Compound
N H
~ –10
O
H
H Br
H Cl
–9
O HO C O H
–7
S
O R
H
H O H O
O
R
R
O
9.2
H H
RO H
~ 24.5
9.4
H R C C N H
~ 25
~ –2.5
H N R R R
~ 10
R
H
~ 25
H N H
28
–1.7
H –1.3
2.0
H F
3.2
O H C O H
3.8
H N H H
~ 20
H C N
H O
10.0
O O C O H
10.2
H H
35
~ 10.3
H N
~36
H
O C O H
H H
R
–3.0
~ –2.0
O H O S O O
~9
H
H H N H H H
~ –3.5
19.2
O
H
R
O O N O H
H H
H 3C H
O ~ –6
O H O S O H O O R S O H O
7.8
S
OH H R
H O
O
H ~ –6
R
R
H
H
O
R
H
H R C NO 2 H H N R H R H N R H H R O
4.2
4.6
RO
S
H
R ~ 11
H
H N
R 38
H
~ 11
H C H H
41
~ 11
H
43
O OR
H H H H C O H H
~ 13
alkenes
43 to 45
15.5
alkanes
48 to 50