Pathwy Edi.docx

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E. PATHWAY

Kuman Salmonella typhi yang masuk ke saluran gastrointestinal

Lolos dari asam

Pembuluh darah limfe

Bakteri masuk usus halus

Peredaran darah (bakterimia promer)

Masuk retikulo endothelial (RES) terutama hati dan limfa

Masuk kealiran darah (bakteremia sekunder)

Berkembang biak di hati dan limfa Empedu Rongga usus pada kel. Limfoid halus

Pembesaran hati

Hepatomegali

Lase plak peyer

Erosi

Dimusnahkan oleh asam lambung

Pembesaran limfe

Splenomegali

Penurunan / peningkatan mobilitas usus

Penurunan / peningkatan peristaltic usus

Endotoksin Terjadi kerusakan sel

Merangsang melepas zat epirogen oleh leukosit Mempengaruhi pusat thermoregulator dihipotalamus

Hypertermi

Resiko kekurangan volume cairan

Nyeri Konstipasi / diare Perdarahan masif

Peningkatan asam lambung Anoreksia mual muntah

Komplikasi perforasi dan perdarahan usus

Ketidakseimbangan nutrisi kurang dari kebutuhan tubuh

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