Pathophysiology Of Perforated Appendicitis With Phlegmon Perforation.docx

Pathophysiology of Perforated Appendicitis with Phlegmon Perforation

PREDISPOSING FACTORS  

Adolescents and young adults Male

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PRECIPITATING FACTORS Obstruction of appendiceal lumen

  

Kinking of appendix Lymphoid hyperplasia Infection

Increased mucinous fluid

Intraluminal pressure increases

Decreased venous drainage, Distention

Pain referred to epigastric area or pre-umbilical area

Decreased oxygen delivery

Ulceration of epithelial lining.

Invasion of Microorganisms

Release of Chemical Mediators

Pain, Swelling, Rebound Tenderness (+) Blumberg, (+) Rovsing, (+) Psoas Sign

Fever

Inflammation

Increased Neutrophils

Pus Formation

Vomiting Appendicitis

Perforation after 72 hours if untreated

Phlegmon formation

Edema

Localized peritonitis

Shallow Breathing

Tachychardia