PATHOPHYSIOLOGY OF DENGUE Bite of a Virus carrying Aedes mosquito Mosquito injects fluid into victim’s skin Virus enters blood stream Infects cells and generate cellular response Initiates immune response (Stimulates release of cytokines) Cytokines destroys cell membrane and cell wall (Viral antigens found in monocytes) Fluid shift
When treated early with doctor prescribed
when illness become severe
medications and managed to prevent the
damage cells due to both cytokines and virus
appearance of other symptoms
fluid shift from ICF-ECF
IVF’s and Electrolyte replacements and precautions patient recovers manifest evanescent rashes
rashes in several areas of the body
bloody vomitus, urine, and stool circulatory collapse shock DEATH