Other Hemolytic Anemia

Other hemolytic anemia’s: Spherocytosis: • Membrane defect → abnormal shape RBC→ hemolysis • May have a hemolytic crisis which can triggered by infection and folate deficiency • May come for splenectomy G6PD Deficiency: • RBC enzyme defect • Can have a hemolytic crisis if exposed to some food and drugs: Fava beans, PNC, Tyhlenol, antimalarial drugs, methylene blue, ASA in large dose • Usually happened 2-5 day after ingestion • May have DIC