Once Upon A Gene
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- Words: 260
- Pages: 22
A tale of two rodents
Once upon a time, scientists did not quite understand how genes worked.
How did they work?
What are they made of?
Are they single molecules?
Or are they large structures with many molecules?
Scientists just didn’t know.
- British scientist and his dog
Mouse :
At left, smooth bacterial colonies* (virulent) Below, rough bacterial colonies* (avirulent)
*representation of colonies on Barbie legs - photos do not display actual colonies
= virulent (disease-causing) in mice
Dead virulent colonies + live avirulent colonies
=
=
+
Dead Virulent
+
Live Avirulent
=
Live virulent !?!?!?
TRANSFORMATION
...JUDGING... We are looking more for the science than the story. - Does your story contain the overall conclusion of the scientists? - Does the story contain HOW the scientists got to their conclusion? - Are there any elaborate details that take away from the science? - Can the listeners figure out the main point of the discovery?!
take out a piece of paper please ! and write your name at the top
1.) Fredrick Griffith found that when he mixed (dead virulent/dead avirulent) with (live virulent/live avirulent) he found, to his surprise, that the mixture killed his test mouse. 2.) Ozzy Avery tested his bacterial juice with enzymes that denatured (broke down) lipids, carbohydrates, protein, RNA and DNA. Why did he do this, what was he looking for? 3.) Hershey and Chase labeled two molecules- Sulfur and Phosphorus, and then made cultures containing one or the other isotope. What did phosphorus have to do with the transforming element? http://www.ncbi.nlm.nih.gov/Class/MLACourse/Original8Hour/Gen etics/nucleotide.html
Once upon a time, scientists did not quite understand how genes worked.
How did they work?
What are they made of?
Are they single molecules?
Or are they large structures with many molecules?
Scientists just didn’t know.
- British scientist and his dog
Mouse :
At left, smooth bacterial colonies* (virulent) Below, rough bacterial colonies* (avirulent)
*representation of colonies on Barbie legs - photos do not display actual colonies
= virulent (disease-causing) in mice
Dead virulent colonies + live avirulent colonies
=
=
+
Dead Virulent
+
Live Avirulent
=
Live virulent !?!?!?
TRANSFORMATION
...JUDGING... We are looking more for the science than the story. - Does your story contain the overall conclusion of the scientists? - Does the story contain HOW the scientists got to their conclusion? - Are there any elaborate details that take away from the science? - Can the listeners figure out the main point of the discovery?!
take out a piece of paper please ! and write your name at the top
1.) Fredrick Griffith found that when he mixed (dead virulent/dead avirulent) with (live virulent/live avirulent) he found, to his surprise, that the mixture killed his test mouse. 2.) Ozzy Avery tested his bacterial juice with enzymes that denatured (broke down) lipids, carbohydrates, protein, RNA and DNA. Why did he do this, what was he looking for? 3.) Hershey and Chase labeled two molecules- Sulfur and Phosphorus, and then made cultures containing one or the other isotope. What did phosphorus have to do with the transforming element? http://www.ncbi.nlm.nih.gov/Class/MLACourse/Original8Hour/Gen etics/nucleotide.html
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