INDEX Generic Name naloxone
Trade Name Narcan
Peak UNK
Onset 1-2 minute
NURS 2236 Clinical Form 3: Clinical Medications Worksheet (You will need to made additional copies of these forms) Classification Dose Route Time/Frequency opioid antagonist 0.4mg IVP PRN Rate: Infuse over 15 seconds or titrate antidote inf to response Duration Normal Dosage range 45 minute 0.4mg q 2-3 min
Why is your patient taking this medication? To reverse the signs of opioid excess
For IV meds, compatability with IV drips and/or solutions Incompatability: None noted
Mechanism of action and indications Reversal of CNS depression and respiratory depression because of suspected opioid overdosage.
Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitivity; cardiovascular disease; patients physically dependent on opioids.
Competitively blocks the effects of opioids, including CNS and respiratory depression, without producing any agonist (opioid-like) effect
Interactions with other patient drugs, OTC, or herbal medicines (ask patient specifically) opioid analgesics; buprenorphine; butorphanol; nalbuphine; pentazocine; propoxphene;
Nursing Process - Assessment (Pre-administration assessment Monitor respiratory rate, rhythm, and depth pulse, ECG, blood pressure; and level of consciousness. tacycardia, hypertension; monitor ECG
Common side effects Hypertension; hypotension; ventricular fibrillation; ventricular tachycardia; nausea; vomiting
Lab value alterations caused by medicine ABGs including PO2, PCO2
Be sure to teach the patient the following about this medication As medication becomes effective, explain purpose and effects of naloxone to patient Report pain that emerges after administration of drug to physician
Assessment Why would you hold or not give this med? Signs of bleeding; naloxone has been associated with abnormal coagulation tachycardia Hypertension
Evaluation Check after giving Patient has adequate ventilation is alert without signifcant pain or withdrawal symptoms