Modifiable Risk Factors Occupational Stress Sns Stimulation Non-modifiable Risk Factors

Modifiable Risk Factors Occupational Stress SNS stimulation Non-modifiable Risk Factors Genetic Predisposition (father’s side) Age (67 y/o) Decreased vascular resistance Aldosterone Epinephrine/ Norepinephrine Arteriolar Constriction ADH Increased Blood volume HYPERLIPIDEMIA Fatty deposition into arterial lumen PRIMARY HYPERTENSION Increased shearing force Damage of arterial endothelial layer Inflammatory response & intravascular clotting Thrombus formation Sclerosis & narrowing of lumen Increased intramural pressure in thrombotic area Dislodgement of thrombus (turns into an emboli) Embolic occlusion in right middle cerebral Transient Ischemia in internal capsule embolic occlusion in myocardial artery CORONARY ARTERY DISEASE (CAD) myocardial ischemia myocardial cells shift to anaerobic glycolysis lactic acid accumulation acute infarction of supplied cerebral area Caudate Nucleus decreased voluntary muscle control dysarthria hemiparesis & hemiphlegia Decreased visual acuity damage to UMN (+) Babinski reflex analgesia of left side of the body internal & external capsule Precentral gyri inferior & middle frontal gyri Unstable Angina superior & inferior parietal gyri superior & middle temporal Decreased auditory perception Atheromatous aorta as seen in the Radiographic tests Disrupted brain cell metabolism Accumulation of water, calcium, sodium Increased ICP Dilation of lateral ventricles in CT scan Corona Radiata Decreased peripheral Vision (Left eye) inflammatory response Localized acidosis & free radical formation CEREBRAL INFARCTION RIGHT BASAL GANGLIA Postcentral gyri