Mbbs Pathology Mcqs

Pathology 2009-2010 MBBS MCQs Shahzad Asghar Arain [email protected] Cell: 92-334-9564004 1. Fibrocystic changes a) is the most common breast disorder in women b) is due to abnormal response to ovarian hormones c) is associated with in-situ carcinoma d) has high risk of developing breast cancer e) is also known as fibroadenoma. 2. Endometrial cancer is

a) b) c) d) e)

associated with use of intrauterine contraceptive device associated with excess estrogen obesity as a risk factor clear cell CA is the most common associated with HPV infection

3. In the area of molecular pathology and molecular diagnosis, a) The detection of monoclonality is essential in diagnosing biopsy samples of breast cancer. b) Microsomal instability are helpful in diagnosing HNPCC c) The detection of monoclonality is essential in diagnosing biopsy samples of lymphomas d) HER2-neu gene detection by FISH test is used to diagnose inherited breast cancer e) FAP is caused by mutations in the mis-match repair genes. 4. Granulomas a) are mainly compose of macrophages, epitheloid cells and lymphocytes b) are always caused by infections c) are mediated by CD4+T lymphocytes d) are mediated by IL-2 and alpha IFN e) always contain area of central necrosis 5. The sequence of metaplasia-dysplasia-neoplasia occurs in the neogenesis of a) squamous cell carcinoma bladder b) carcinoid of the small intestine c) adenocarcinoma of the Barret's oesphagus d) squamous cell carcinoma of the lungs e) malignant lymphoma 6. In acute inflammation a) decreased blood flow to affected part b) increased vascular permeability to proteins c) is associated with local 5 hydroxytrytamine release d) caused by mechanical trauma e) a manifestation of the ability of normal tissues to respond to damage 7. Regarding Osteoarthritis a) cartilage fibrillation b) pannus formation c) eburnation of bone d) herberden's nodes e) osteophyte formation 8. Macrophages a) play a role in graft rejection

b) c) d) e)

are involved in antigen recognition Have membrane receptors for Fc fragment of antibodies Is involved in type 4 hypersensitivity Have no phagocytic properties

9. Low grade lymphomas: a) Incurable b) monoclonal proliferation of large lymphoid cells c) clinically aggressive 10. 11. Which of the following helps in the grading of a tumor? a) the presence or absence of metastases in the lymph node b) the degree of differentiation c) the presence of tumor necrosis d) mitotic activity e) the presence of cells in the vascular spaces 12. Successful healing of long bones depends upon: a) apposition of the fragments b) Surgical removal of the hematoma c) Free mobility of the limb d) The absence of infection e) Elevation of the limb 13. Small cell carcinoma of the lung is: a. Is not associated with cigarette smoking. b. Is usually found in the periphery of the lung. c. Is more common in women than men. d. Often produces ectopic hormones e. Has a poor prognosis. 14. Adult respiratory distress syndrome: a) pulmonary edema is a feature b) hyaline membrane is present in alveoli c) has a high mortality d) associated with acute pancreatitis e) can occur following diffuse alveolar injury 15. 16. Fall in blood pH from 7.40 to 7.10 a) represents an approximate doubling of H+ concentration b) characteristically caused by persistent vomiting c) characteristically caused by hyperventilation

d) can be accompanied by elevated serum potassium e) is incompatible with life 17. What of the following causes elevated total CSF protein: a) CNS tumour b) CVA c) Epilepsy d) Viral meningitis e) CNS trauma 18. H Pylori a) associated with gastric carcinoma and lymphoma b) causes a chronic lymphoid infiltration c) is a urea-producing organism d) is usually found in areas of intestinal metaplasia e) causes a chronic gastritis by invading the mucosal epithelium 19. Pseudomembranous Colitis a) caused by clostridium difficile toxin b) is present in immunosuppressed individuals c) toxin mediated injury causes epithelial shedding and necrosis d) pseudomembranes present by desloughing of epithelium e) associated with antibiotic use 20. Concerning SLE a) circulating immune complexes responsible for glomerulonephritis b) absolute increase in T suppressor cells c) renal biopsy seldom required for directing therapy d) renal biopsy includes active diffuse proliferating glomerulonephritis e) ITP can be initial manifestation of SLE Please feel free to contact for further data of fallowing universities Fees, admission, classes, environment http://pakdata.net [email protected] • • • • • • • • • •

National Defence University, Islamabad Virtual University of Pakistan, Lahore National University of Science and Technology, Rawalpindi Quaid-e-Azam University, Islamabad Pakistan Institute of Development Economics, Islamabad Pakistan Institute of Engineering & Applied Sciences, Islamabad National University of Modern Languages, Islamabad International Islamic University, Islamabad Institute of Space Technology (IST), Islamabad Federal Urdu University of Arts, Science and Technology, Islamabad and Karachi

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COMSATS Institute of Information Technology, Islamabad Bahria University, Islamabad Allama Iqbal Open University, Islamabad Air University, Islamabad Riphah International University, Islamabad National University of Computer and Emerging Sciences, Islamabad Foundation University, Rawalpindi Center for Advanced Studies in Engineering, Islamabad University of Azad Jammu and Kashmir, Muzaffarabad Mohi-ud-Din Islamic University, Nerian Sharif AJK Al-Khair University (Mir Pur AJK), Bolan University of Medical & Health Sciences, Quetta Balochistan University of Engineering and Technology, Khuzdar Balochistan University of Information Technology, Engineering and Management Sciences, Quetta Lasbela University of Agriculture, Water & Marine Science, Lasbela Sardar Bahadur Khan Women University, Quetta University of Balochistan, Quetta Institute of Management Sciences (IMSciences), Hayatabad Frontier Women University, Peshawar Gomal University, Dera Ismail Khan Islamia College University, Peshawar Kohat University of Science & Technology, Kohat Khyber University of Medical and Health Sciences, Peshawar NWFP Agricultural University, Peshawar Pakistan Military Academy, Abbotabad The University of Science & Tecnology, Bannu University of Engineering and Technology (NWFP), Peshawar University of Hazara, Hazara University of Malakand, Chakdara University of Peshawar, Peshawar Qurtaba University of Science & Information Technology, D. I. Khan, Peshawar CECOS University of Information Technology and Emerging Sciences, Peshawar City University of Science and Information Technology, Peshawar Gandhara University, Peshawar Ghulam Ishaq Khan Institute of Engineering Sciences and Technology, Swabi Northern University, Nowshera Preston University, Kohat Sarhad University of Science and Information Technology, Peshawar Abasyn University, Peshawar Gandhara College of Arts, Peshawar Karakurum International University, Gilgit Allama Iqbal Open University, Gilgit Bahauddin Zakariya University, Multan

King Edward Medical University, Lahore • •

Fatima Jinnah Women University, Rawalpindi Government College University, Lahore

Lahore University of Management Sciences • • • • • • • • • • • • • • • • • • • • • • • •

Government College University, Faisalabad The Islamia University of Bahawalpur, Bahawalpur Kinnaird College for Women, Lahore King Edward Medical College, Lahore Lahore College for Women University, Lahore National College of Arts, Lahore National Textile University, Faisalabad University of Agriculture, Faisalabad University of Arid Agriculture, Rawalpindi University of Education, Lahore University of Engineering and Technology, Lahore, Faisalabad University of Engineering and Technology,Taxila University of Health Sciences, Lahore University of Gujrat, Gujrat University of the Punjab, Lahore, Gujranwala University of Sargodha, Sargodha University of Veterinary and Animal Sciences, Lahore Virtual University of Pakistan, Lahore Hajvery University, Lahore Beaconhouse National University, Lahore Forman Christian College, Lahore GIFT University, Gujranwala Imperial College of Business Studies, Lahore Institute of Management Sciences, Lahore, Pak-AIMS, Lahore

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Lahore School of Economics, Lahore Lahore University of Management Sciences, Lahore Minhaj International University, Lahore National College of Business Administration and Economics, Lahore School of Business & Commerce, Rawalpindi University Of Management and Technology, Lahore University of Central Punjab, Lahore University of Faisalabad, Faisalabad University of Lahore, Lahore University of South Asia, Lahore Superior University, Lahore International Islamic University, Bahawalpur University College Lahore, Lahore University of Munawwar-ul-islam.Gujrat Bahria University, Karachi Campus Dawood College of Engineering and Technology,Karachi Dow University of Health Sciences, Karachi Institute of Business Administration, Karachi Liaquat University of Medical and Health Sciences, Jamshoro, Hyderabad Mehran University of Engineering and Technology, Jamshoro, Hyderabad NED University of Engineering & Technology, Karachi Pakistan Naval Academy, Karachi Quaid-e-Awam University of Engineering, Science and Technology, Nawabshah Shah Abdul Latif Bhitai University, Khairpur Sindh Agriculture University, Tandojam Institute of Business Administration (IBA) Sukkur University of Karachi, Karachi University of Sindh, Jamshoro, Hyderabad Aga Khan University, Karachi Baqai Medical University, Karachi Dadabhoy Institute of Higher Education, Karachi DHA Suffa University, Karachi Greenwich University, Karachi Hamdard University, Karachi Indus Institute of Higher Education, Karachi Indus Valley School of Art and Architecture, Karachi National University of Computer and Emerging Sciences, formerly FAST Institute of Computer Science Karachi Campus Institute of Business & Technology (BIZTEK), Karachi Institute of Business Management, Karachi Iqra University, Karachi Isra University, Hyderabad Jinnah University for Women, Karachi Karachi Institute of Economics & Technology (PAF KIET), Karachi KASB Institute of Information Technology, Karachi

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Mohammad Ali Jinnah University, Karachi Nazeer Hussain University, Karachi Newports Institute of Communications and Economics, Karachi Preston Institute of Management Sciences and Technology, Karachi Preston University, Karachi Shaheed Zulfiqar Ali Bhutto Institute of Science and Technology, Karachi Sir Syed University of Engineering and Technology, Karachi Textile Institute of Pakistan, Karachi University of East, Hyderabad Ziauddin Medical University, Karachi