Kayleen Toxicology
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BY Kayleen Sinfellow
What Is toxicology • It Is the study of the adverse effects of chemicals on living organisms.
Toxicologist Study • Conducting chemical research for military and medical uses, such as protecting people from radiation, chemicals and biological agents • It is the study of symptoms, mechanisms, treatments and detection of poisoning, especially the poisoning of people. • The testing evaluates the biological response of living organisms to different routes and durations of exposure to a substance.
Toxicology Breakthroughs • Toxicology's High Tech Future • Five years ago, CNR’s Nutritional Sciences and Toxicology (NST) department looked at its molecular toxicology group and asked: What does the future of our field look like? • The answer, they realized, was a shift toward “systems biology”—that is, looking at the complex interactions of metabolic, genetic, protein, and cellular elements with the goal of modeling entire systems. • Such an approach requires serious data crunching. To keep the undergraduate curriculum up-to-date, the department turned to adjunct professor Dale Johnson, a former vice president for research and development at the biotech giant Chiron, and current CEO of a biotech startup called Emiliem. Johnson designed a course in computational toxicology to teach students the techniques and technologies required to analyze toxins, from pharmaceuticals in the body to chemicals in the environment. In the lab portion of the class, students use the heavy-duty computing power of CNR’s Geospatial Imaging and Informatics Facility.
Toxicology Breakthroughs •
In the wake of a toxic spill or chemical attack, knowing which areas are contaminated and which are not is an important part of getting operations back to normal. MRI, as a subcontractor to Hamilton Sundstrand for the U.S. Department of Homeland Security, helped engineer a mobile laboratory that can go virtually anywhere and quickly analyze, with tremendous precision, any type of sample (such as plant, soil, water, air) for contaminants. This state-of-the-art system is called PHILIS, for Portable High-Throughput Integrated Laboratory System, and is designed to process 500 samples per day
What Is toxicology • It Is the study of the adverse effects of chemicals on living organisms.
Toxicologist Study • Conducting chemical research for military and medical uses, such as protecting people from radiation, chemicals and biological agents • It is the study of symptoms, mechanisms, treatments and detection of poisoning, especially the poisoning of people. • The testing evaluates the biological response of living organisms to different routes and durations of exposure to a substance.
Toxicology Breakthroughs • Toxicology's High Tech Future • Five years ago, CNR’s Nutritional Sciences and Toxicology (NST) department looked at its molecular toxicology group and asked: What does the future of our field look like? • The answer, they realized, was a shift toward “systems biology”—that is, looking at the complex interactions of metabolic, genetic, protein, and cellular elements with the goal of modeling entire systems. • Such an approach requires serious data crunching. To keep the undergraduate curriculum up-to-date, the department turned to adjunct professor Dale Johnson, a former vice president for research and development at the biotech giant Chiron, and current CEO of a biotech startup called Emiliem. Johnson designed a course in computational toxicology to teach students the techniques and technologies required to analyze toxins, from pharmaceuticals in the body to chemicals in the environment. In the lab portion of the class, students use the heavy-duty computing power of CNR’s Geospatial Imaging and Informatics Facility.
Toxicology Breakthroughs •
In the wake of a toxic spill or chemical attack, knowing which areas are contaminated and which are not is an important part of getting operations back to normal. MRI, as a subcontractor to Hamilton Sundstrand for the U.S. Department of Homeland Security, helped engineer a mobile laboratory that can go virtually anywhere and quickly analyze, with tremendous precision, any type of sample (such as plant, soil, water, air) for contaminants. This state-of-the-art system is called PHILIS, for Portable High-Throughput Integrated Laboratory System, and is designed to process 500 samples per day
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