Jan-2009

NEWS LETTER OF ARMARC JAN -2009

Editorial The development of civilization brought in new thoughts of living together from the nomadic form. The social system of life style brought in the formation of countries, racism etc. it also gave birth to luxury with the inventions and discoveries. These luxuries made name more and more comfortable and easier means to meet his ends. It is agreeable that even today we are the puppets in the hands of these objects of luxury for example electricity, vehicles, computer fast foods etc which was absent in the age old day of civilization. The absence of these materials led them to undergo utmost physical exertion. This not only helped in maintaining a good physique but also helped in proper functioning of the bodily organs. Unlike today the irregularity in the work field along with competitions giving rise are more of sedentary in nature gives a considerable exertion mentally but not to the physical constituent of man. The development also brought with it various diseases like AIDS, Diabetes, Skin diseases etc. The present situation has only led to various diseased states. No matter we discover a large spectrum of medicines and equip ourselves with various kinds of measures to combat and conquer the innumerable disease that exist today. Still we lack the capacity to achieve the complete health under the present conditions. Can we achieve the complete Health? If yes how? It is possible if we forego the luxurious life that had been adopted. Is it possible to do so? It is big question that comes to our mind especially when we are deprived of it. No we cannot live at present the reason is that we are very much used to the present conditions and mentally we are not ready to be away from these

Vol 1.79 luxuries. It is to really happen then there should be complete blackout of these entities. Only when we are mentally prepared for taking up the task, then it is possible to live. Though the old lifestyle was unisivilized in view of the present day modern world still it was more healthy and peaceful than the present.

Wishing you a New Year filled with new hope, new joy and new beginnings

 

 

In This Issue 1. Surtavarta and its Ayurvedic management. 2. Obesity: a short Description. 3. Quality assessment of roots of Brihatpanchamoola from different agroclimatic zones of Gujrat. 4. Formulation Profile (Series-A/2) VASAKASAVA 5. Herbal Drug Profile (Series-A/3) BRINGARAJ. (Eclipta alba)

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“SURYAVARTA” AND ITS AYURVEDIC MANAGEMENT DR SUBRAT KUMAR NAYAK, M.S. (Ayu) Reader,S.V.M.Ayurvedic Medical College.ILKAL-Karnataka INTRODUCTIONSuryavarta which is also known as

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JAN -2009 This shrotavarodha causes vitiation of Vata dosha further. So when Vata dosha gets vitiated, that starts pain in the head in the morning. Gradually the pain increases in intensity till the noon. In noon, due to heavy heat, the kapha dosha starts dissolving which causes relax in shrotavarodha and when shrotavarodha gets released,

Bhaskaravarta in Ayurvedic classics, which is a common Vata dosha also gets pacified which causes relieve in disease usually occurs after the age of 15, but may affect pain by the evening. even children aged 5 years. In ayurvedic classics CAUSES: Suryavarta is described under the heading of Shiroroga. According to Carakacarya, vegavarodha or In all major texts of Ayurveda like Carak, Sushruta and suppression of the urges and Ajirna or Indigestion Vagbhatta the description of Suryavarta is available. are considered as the two important causes in The disease has got its own importance as it may cause forming the disease Suryavarta. According to him, lot of complications if not treated in time. As per the Vegavarodha and Arjina these two factors cause signs and symptoms it has got a close relation with vitiation of Rakta and Vata dosha, which affect the Frontal Sinusitis in modern medical science, which MASTISKA (the air Sinuses) causing Suryavarta. occurs due to the infection of Para nasal sinuses According to Sushruta it is a tridoshaja vyadhi. particularly, the Frontal Sinus. According to Vagbhatta it is a Pitta predominant Vata associated tridoshaja vyadhi. WHY SUCH NAME? According to modern medical science it is due to “SURYAMIVAVARTO BHRAMANAM YASYA SA the infection of Para nasal sinuses particularly the VIKARAH SURYAVARTAH” The disease is named as Suryavarta because Frontal sinus. The infection usually spreads from of its relation with the movement of lord Surya or Sun. the nasal infections. Usually the infection caused In this disease particularly the patients get mild pain in by respiratory tract organisms like Streptococci, the head, which starts in the morning. As the sun goes Pneumococci, Micrococus catarrhalis, up , in the sky the pain increases in intensity and by the Staphylococci or Haemophilus influenza etc. noon or midday the pain becomes worse or un tolerable. PREDISPOSING FACTORS: As the sun goes down the pain decreases dramatically Nasal infection like common cold and influenza. in night it becomes very less. Due to this peculiar relation Nasal allergy leads to blocking of the nose and of this disease with the movement of Sun, the disease is obstruction to the drainage of sinuses. named as Suryavarta. Forcible blowing of the nose- pushes the infection REASON OF THE SURYAVARTA: fro nose into the sinuses. In Ayurveda night or Ratri Kala is considered Swimming and diving in water. as cold or shitala in nature and it is predominant in Dental infection. Tamo guna also. So due to this shitala guna, Lowered resistance like in influenza, measles, shrotavarodha or obstruction in the channels in shira chickenpox etc. Atmospheric pollution that promotes nasal infection. pradesh takes place (due to Kapha vitiation).

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SIGNS AND SYMPTOMS: ♦ It is a special type of headache (Shira shoola) that changes according to the Sunrays. ♦ The headache starts in the morning, gradually increases up to noon, maximum at noon or midday and gradually decreases up to night. The pain is experienced more at eyes, Bhru (root of the nose), Sankha pradesh and lLalata pradesh. ♦ Tenderness is tested on the medial part of the floor of the sinus above the inner canthus of the eyes. ♦ Oedema of the sinus and upper eyelid is rare. TREATMENT: ♦ NIDANA PARIVARJANA- Nidana parivarjana or avoidance of the disease producing factors are considered as the first line of treatment in all diseases in Ayurveda.So disease producing factors are to be avoided first. ♦ TRIDOSHA HARA CHIKITSHA-Tridosha nasak Chickitsha is to be followed, as it is a tridoshaja vyadhi, particularly Pitta-Vatta hara chikitsha is advocated. ♦ Oral intake of Ghee and Guda helps in this condition. ♦ Oral administration of Ghee after meals is advised. ♦ Jangala mamsa rasa is added to meals. ♦ Shiro vasti with Chatursneha. ♦ Medicated liquid for Kavala (Gargling) NASYA-Nasya is considered as the most effective treatment for all type of shiroroga. Kshiri Sarpi Nasya or Nasya with Bhringraj swaras with goat’s milk or nasya with Apamarga swarasa or nasya with Katphala churna helps in this condition. LEPAS- Surya mukhi beeja + Suryamukhi Swarasa for external application. Sarivadi lepa- Sariva + Uthpala + Kustha + Yasthimadhu should be grinded with Kanji and Applied on the head. Local application of Taila with milk also helps in this condition. ORAL MEDICATION♦ Suryavarta ras- 1 tab twice daily. ♦ Shirashuladi vajra vati- 1 tab twice daily. ♦ Chandanadi vati ♦ Vata vidhwamsini vati ♦ Danti bhasma 125mg + Pravala Bhasma 125 mg with ghee ♦ Godanti bhasma + Spatika bhasma equal quantity.

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JAN - 2009 (Continued from December edition.....)

Obesity: A Short Description Prof. (Dr.) Rashmirekha Mishra Prof. (Dr.) Taranikanta Mohanta Department of Kayachikitsa ,Dean, PG Centre, ALNRM Ayurvedic Medical College, Koppa Nidana Madhava nidana reveal with the different causative factor of sthaulya as: 1 Insufficient exercise 2. Day sleep 3. Excessive sweet and shleshma vardhaka ahara means particularlya. Different types of sweet preparations, ice cream, payasa etc. b. Excessive oily food or fast food c. Excessive carbohydrates like rice, potato, root vegetables d. Frequent taking of more amount of food e. More meat, alcohol etc. 4. Other causes: a. Genetic b. Due to defective mechanism of thyroid gland c. Age factors- Generally after the age of 40 d. Drug induced Medoroga or sthaulya occurs due to taking place of more Medodhatu vriddhi srotas avarana, the result what other dhatus remain deprived of their required nourishment. Patient becomes inactive or loss of enthusiasm. This is also due to sedentary habit means more intake of food rich in protein and fatty substances with sufficient rest (day sleep) but without having exercise. Means storage of energy in terms of less energy consumption than gaining brings out the abnormal growth of body fat and this is Medoroga. It also plays an important role for causing the ischemic heart diseases. The data shows remarkably increasing morbidity and mortality rate followed by obesity. Excessive deposition of fat not only occurs in portions of heap, belly, and breast but also in heart, brain and kidney which is known as ‘Trimarma’, the most risk factors.

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Medavriddhi is the combined effect of Kapha dosha and Medo dhatu vriddhi. If we consider Panchabhoutika sangathana of each, we find: Kapha dosha = Prithvi + Jala Medodhatu = Prithvi + Jala + Agni. Accoding to the principle of Samanya vishesha siddhanta Medavriddhi is credited to excessive use of Kaphavardhaka nidana. As per the Charak Sutra 12/ 5, with Medovriddhi kapha remains in vriddhavasta leading to alasyata, tandra, loss of enthusiasm, inactivity followed by some Kaphaja vikara like asthma, prameha, vicharchika and dhamani pratichaya etc. xÉqÉaÉÑhÉÉprÉÉxÉÉå ÌWû kÉÉiÉÔlÉÉÇ uÉ×ήMüÉUhÉqÉç || - cÉ. xÉÑ. 12/5 It is important to note that kapha dosha has a predominant role in medoroga but agnimandyavasta is absent. Normally Medarogi gets more appetite, more digestion capacity but the tiredness with less work. Regarding this, the Samprapti as per the Madhava nidana suggests that Medovriddhi leads to Avarana of srotas which hampers the movement of vata including the improper circulation of poshaka tatwa. It leaves to stagnation of vata in kostha but stimulation of agni and the result is more hunger and first digestion. Even after digestion, the annarasa nourishes to more Medadhatu than others creating Sthoulyata. This improper nourishment of other dhatu makes the person feel more tiredness. This is the cause why a corpulent person likes to take more rest and eat. These are the reasons behind the not toleration of fasting by obese as kosthagni remains very active and without food it burns the dhatus. Madhava nidana exposes burning of body of Sthula person by vata and agni when food is not supplemented. As this burning is co-related with burning of forest, hence it may also regarded as Bhasmagni condition.

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JAN -2009 3. 4. 5. 6. 7. 8. 9.

More tiredness with less work Probability of suffering from Kaphaja vikara. Less life-span as per the Charak Excessive sweating with foul body-smell Excessive thirst Excessive hunger Sexual inactivity

Influence of BMR (Basal Metabolic Rate): The largest component of energy consumption is Basal Metabolic Rate (BMR). It is related with height and weight. It declines with age and is found less in women than the men. The BMR of obese person is also less. Many obese people questions that they do not eat more than their lean counterparts but still becomes worry with the report that inability to loose weight on a low energy diet. The answer is with condition survey report unveiling the instances of the development of obesity due to a metabolic defect causing reduced energy expenditure as a result of metabolic enzymatic defect. Obesity is also associated with a number of other metabolic disturbances as: 1. Diabetes mellitus- This is most common among obese people however, fortunately some obese people escape from it. 2. Elevated level of cholesterol- It is often associated with it in blood plasma. 3. Stones in gall bladder- This alteration is more frequent in obese person than that of normal weight. 4. Artherosclerosis- Usually obese persons get deposited with cholesterol in the inner lining of the arteries producing this. 5. High Blood Pressure- Obese people more prone to high blood pressure than normal one. Lakshana: 1. The declined normal activity of person leading 6. Angina Pectoris and Cardiac Failure- as the work load of heart increases by the extra mechanical effort to inability of doing work with normal speed as needed the overweight body an in overcoming walking, running, talking etc.. hypertension. So with the tendency to Atherosclerosis 2. Unpleasant look due to abnormal deposition in coronary arteries accounts for Angina Pectoris of of fat cardiac failure in obese people in middle life.

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7. Obese persons are likely to have Hypertriglyceridemia and low HDL (good) cholesterol, which is a factor for increasing coronary artery disease. Simultaneously High LDL (Bad). 8. Obesity raises the estrogen level which is a causative factor for Breast cancer. Diagnosis Following measurements for the diagnosis of obesity are suggested as: 1. It is made by observation of fat accumulation and the measurement is referred to relation of height and weight i.e., Body Mass Index (BMI) which is usually expressed in Kilogram/meter2. For a normal person it is suggested to be 25 kg/m2 while more than 27 kg/m2 and less than 27 kg/m2 imparts the health risk. 2. It is also done through skin-fold measurements. 3. Various body circumferences are also measured for the purpose. The etiology of obesity is complex and incompletely understood. A central or visceral accumulation of fat is more risky than the accumulation of fat in subcutaneous tissues which is usually due to accumulation of excess energy in forms of triglycerides in adipose tissue. The two sides of energy equation that is intake and consumption are finely regulated by neural and hormonal mechanism. It is now established fact that adipocytes communicate with the satiety center in the brain by secreting a polypeptide hormone called Leptin and output of leptin is regulated by the adequacy of the fat stores. Hence with more fat storage leptin secretion is stimulated and the hormone travels to the hypothalamus.

Treatment:

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JAN -2009 iÉiÉç qÉåSÉÅÌlÉsÉ zsÉåwqÉlÉÉzÉlÉ xÉuÉïÍqÉwrÉiÉå | - A. WØû. 14/21 The treatments reducing meda, anila and shleshma are desirable. The principle behind the treatment is consumption of such food which satisfies the satiety centre but is with lower calorific values. Specific suggested foods are use of husks, barley etc. in place of rice. Among the pulses Mudga is considered best than the other types. The other treatments usually prescribed include: 1. Advice to use Triphala churna powder 6gms 2 times with madhu regularly. 2. To take Guduchi swarasa or the decoction along with Madhu. 3. Habitual intake of Patoladi Kwatha, Kiratatiktadi Kwatha like anyone Tikta Kashaya in amount of 50 ml twice a day 4. Use of Yava and Godhuma more to satisfy the hunger but giving fewer calories. 5. Less intake of regular food and doing of exercise. 6. Daily licking of Amalaki churna with honey and Yava churna. 7. 1 spoon Haridra churna in empty stomach. 8. Daily use of ½ tea spoon of Methi churna in empty stomach. 9. Haritaki alone or along with Trikatu churna, Shigru, Vidanga, Yavani, Dhanyaka, Chitraka or Yava is successful medicine for Sthaulya. 10. A study exposed that use of Takra for 1 month and sleeping on the floor and taking bath thrice a day may reduce about 5 kg of body weight within 1 month. 11. Daily use of Lashuna (tender 2-3 pieces) is helpful for reduction of weight and proper function of heart. • In an observation it is found that garlic paste in a dose of 500 mg with water daily gives result in erectile dysfunction.(According to the survey done by the Natural Herbs Society on thousand patients on Obesity) • Guduchi satwa 500 mg with water twice a day can be used. • Use of Mustard oil and Mustard in food is helpful. • Use of hot water always is very much beneficial. •Mild exercise is must like walking, jogging should be avoided because on the load of heart circulation

MüÉzrÉï q Éå u É uÉUÇ xjÉÉæ s rÉÉiÉç lÉÌWû xjÉÉæ s rÉxrÉ pÉå w ÉeÉqÉç | oÉ×ÇWûhÉ sÉÇbÉlÉÇ uÉÉÅsÉqÉÌiÉqÉåSÉåÅÎalÉuÉÉiÉÎeÉiÉç || - A. WÛû. Present shloka exposes that emaciation is better than corpulence and there is no treatment for obese. Neither Brumhana nor Langhana is enough to vanish excess of fat, digestive activity and vata. Obesity can be cured by use of Ruksha and Tikta rasa present with increases. food and medicines.

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6

JAN -2009

(Continued from December edition.....)

QUALITY ASSESSMENT OF ROOTS OF Brihatpanchmoola FROM DIFFERENT AGROCLIMATIC ZONES OF GUJARAT 1. Ajit Lingayat Technical Expert, KLE’S Ayurvedic Pharmacy, Belgaum 2. Dr. A. P. Singh, IFS, Ex-Director, ISM&H,Gujarat 3. Dr. Prashant Kumar Jha The comparison of presence of chemical constituents of different Rf can be cited as given in table no. 7 Rf Sasangir Gandhinagar Vansda Rajpipla 0.06 + + + 0.28 + + + + 0.31 + + 0.42 + + + + 0.47 + + 0.57 + + + 0.63 + + + 0.68 + + + 0.79 + + + 0.85 + + + 0.95 + Illustration of Rf values of Shyonaka The maximum percentage area covered by the spots on the plate by samples collected from different agroclimatic zones showed the variations as for the samples of Sasangir, Gandhinagar, Vansda and Rajpipla these variations were with the samples of Rf 0.68, 0.68, 0.47 and 0.47. While observing the Patala collected from Gandhinagar, 8 spots were found. The Rf were respectively at 0.08, 0.31, 0,35, 0.54, 0.58, 0.63, 0.72 and 0.79. The percentage area covered was maximum in case of constituent bearing Rf 0.35 i.e., 29.32% which exhibited the intensity and concentration of this chemical constituent in more amount than the others. The least percentage area covered was of the compounds having Rf 0.08 i.e., 01.23%. The sample collected from Vansda and Rajpipla exhibited five and seven spots respectively.

The comparison of presence of chemical constituents of different Rf can be cited as given in table no.- 8 Rf Gandhinagar Vansda Rajpipla 0.08 + + 0.31 + + + 0.35 + + 0.54 + + + 0.58 + + 0.63 + + 0.72 + + 0.79 Showing Rf values of Patala The maximum percentage area covered by the spots on the plate by samples collected from different agroclimatic zones showed the variations as for the samples of Gandhinagar, Vansda and Rajpipla these variations were with the samples of Rf 0.35, 0.54, and 0.54. Gambhari collected from Sasangir was observed, it showed 9 spots under 580 nm while 3 in 366 nm. Out of 9 spots observed, the Rf were respectively 0.06, 0.33, 0.45, 0,58, 0.61, 0.66, 0.78, 0.85, and 0.93. The percentage area covered was maximum in case of constituent bearing Rf 0.45 i.e., 39.59% which exhibited the intensity and concentration of this chemical constituent in more amount than the others. The least percentage area covered was of the compounds having Rf 0.58 i.e., 3.10%. The sample collected from Gandhinagar showed seven spots while those collected from Vansda and Rajpipla exhibited five spots each.

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Formulation Profile (Series-A/2) VASAKASAVA Dr. J. Clarence Davy. Guid:Dr. Damodar Pande. Dr. Dinesh Kumar Mishra. M.D (Ay). Dr. Jayaraj .M, Dr. Mahesh.Madalageri Various sandhana Kalpanas are mentioned by the Acharyas, among them Asava and Arishta are popular in the field of treatment. Sandhana Kalpana proves more beneficial as it is having medicinal as well as nutritive value; important one is that the self generated alcohol during the Sandhana prakriya act as solvent for maximum extraction of principles from raw drugs and also as preservative. The Svayathuhara property of Vasa can be seen in Pranavaha srothus because in almost all respiratory disorders the alveoli, bronchi etc are well swollen thereby causing difficulty in breathing. So this Svayathuhara property of vasa can be expected in other tissues also. so based on this idea the drug-Vasa has been selected for the present study. Reference1. Gada Nigraha. Asavarishta Shastra. 6/152-154 2. Yogaratnakara. Shotha Chikitsa Adhikara, 78-80 IngredientsKwatha - Vasa Panchanga - 9.6 Kg. Jala - 24.576 Lit. Reduced to 6.144 Lit. Madhura Dravya : Guda - 4.8 Kg. Sandhaneeya Dravya-Dhataki Pushpa -384 g Prakshepa Dravyas(Twak ,Ela, Patra ,Kesara, Kankola, Shundi, Maricha, Pippali, Toya (Hreebera) each drug – 48 g. Therapeutic Use- This preparation is mentioned for Svayathu. Report of Analytical StudyParameters

Vasakasava

Vasakasava (With Vasa

(with Vasa Kwatha) Putapaka Swarasa) Description Ash

Aromatic brown liguid Aromatic brown liguid with sweet taste.

with sweet taste.

1.78 % w/w

2.29 % w/w

Acid insoluble ash 0.13% w/w

Nil

Specicific gravity 1.1264

1.1247

0

at 25 C Solid content

30.08 % w/w

33.89 % w/w

pH

3.89

5.33

Alcohol content

8.31 % w/v

8.31 % w/v

JAN -2009

Herbal Drug Profile (Series-A/3) BRINGARAJ Eclipta alba Compositae 1. Prof. M. Vidyasagar 2. Prof. K.S.Sanjay 3. Dr. Hari Venkatesh 4. Dr. Prashant Kumar Jha Department of Dravyaguna MACROSCOPIC : Root - Well developed, a number of secondary branches aries from main root, upto about 7 mm. in india, cylindrical, greyish. Stem - Herbaceous, branched, occasionally rooting at nodes, cylindricle or flatte, rough due to oppressed white hairs, node distinct, greenish, occasionally brownish. Leaves - Opposite, sessile or subsessile, oblong, lanceolate, 2.5 - 8.5 cms long, 1.2 – 2.3 cm wide, sub-entire, sub-acute or acute, strigoes with appressed hairs on both surfaces. Flower – Ligulate, ligule small, spreading, scarcely as long as bracts, not toothed, white. Fruit – Achenial cypsella, one seeded, cuneate, eith a narrow wing, covered with warty excrescences, brown. Seed – 0.2 – 0.25 cm long, 0.1 cm wide, dark brown, hairy and non endospermic. CHEMICAL CONSTITUENTS: The presence of Alkanes hertriacontan-1-01 and hepatacosan-14-01 and Alkynes – tetradeca-46-diene-8-10-12 triyne, trideca-1-ene-3-5-7-9-11pentayne, trideca-cis-1-7-diene-3-5-9-11-tetrayne-8methylesulfonate and trideca -trans-1-7-diene-3-5-911-tetrayne-5-methylsulfonate in the root of Eclipta alba. The Leaf contains Triterpenes - Eclalbasaponins I to X8, triterpene acid glucoside9, Ecliptasaponin A18, Ecliptasaponin B18, Ecliptasaponin D16 and oleanolic acid17, and Steroidal alkaloids – Ecliptalbine and Verazine and its derivatives19.

JAN -2009

RNI Regd No. KARENG/2002/7924

ACCORDING TO CLASSICAL USES: Kasa ,Krimia, Shvasa ,Kustha ,Dantya ,Pandu Raktapitta ,Amlapitta ,Shirorog ,Jwara ,Nadivran Swarabhed ,Hardroga ETHNOMEDICAL USES Antiasthamatic , Antidiabetic,Anti-inflammatory Antileprotic , Antioedemic, Bronchitis , Cholagogue Emetic , Eye diseases, Haemostatic, Headache, Hepatitis , Haircare , Jaundice , Skin disease ,Spleen disorder, Tonic , Toothache. DOSE: Juice : 3-6 ml. Decoction : 12-36gm powder. Churna : 3-5gm.

PRINTED MATTER/BOOK POST

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New Reseacrhes In Medical Science 1. The antiplatelet drug clopidogrel requires activation by cytochrome P-450 (CYP) enzymes. This study shows that CYP polymorphisms that reduce clopidogrel activation result in reduced antiplatelet effect and less clinical benefit in patients with acute coronary syndrome. 2.Intensive glucose control in a population of subjects with poorly controlled type 2 diabetes had no significant effect on major cardiovascular events, mortality, or microvascular complications.

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For All Phamacopoeial Analysis And Standardization of Single Herb As Well As For Formulation Contact: Dr. Prashant Kr. Jha CIPR, DIM, PGDEE, M.Sc., Ph.D. Quality Control Laboratories, ALNRao Memorial Ayurvedic Medical College, Koppa

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Editor: Prof (Dr.) M.Vidyasagar & Co-Editor: Dr.Prashant kumar Jha Research Co-ordinator Dr. Mahesh.M.Madalageri Printed and Published by ARMARC on behalf of Honourable A. Ramesh Rao, Koppa, Chikmagalur Dt., Karnataka - 577126, India

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