Intestine Transplant Project

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intestinal transplants Angela Ortyl and Bridget Doyle

the intestines The intestines are part of the digestive system. They are located in the abdominopelvic cavity. The intestines is where most of the digestion occurs. They are responsible for creating solid and liquid waste.

How many are done? •

200 hundred intestinal transplants done in 2007 in the United States. 90% survive the first year.



63% survive for 3-5 years.

The Waiting List •

140 children waiting for a transplant. 253 people died while waiting for a transplant.



379 out of 1000 patients die.

Who needs it? •

Irreversible intestine failure. Short gut syndrome



Malabsorption syndrome



Mortality 10 disorder



Tumors of intestinal mesentery.

Who can’t get it? •

Life expectancy of less than 5 years due to age related dibilitation Ability to ingest oral nutrition



Unresectable malignancy



Serious, uncontrolled psychiatric illness Neurological illness unrelated to disease



Drug or alcohol addiction



HIV positive Active and/or life threatening infection







Severe body/organ system disease (unrelated to one being treated) Compromised cardio-pulmonary function Inability or unwillingness to comply with follow up requirements.

Where can it be done? •

UCLA transplant center



Children’s Hospital of Pittsburgh

How long does it take? •



The intestine transplant takes 6-12 hours depending on how much is needed to be transplanted. To give a part of intestine, takes around 3 hours.

How much does it cost? It cost approximately $275,000 to get an intestinal transplant

Dead or alive? •

To give a whole intestine you have to be dead



To give part of an intestine you can be alive

Anti-rejection drugs.. •

Tacrolimus, which is the most commonly used drug Corticosteroids



Mycophenolate mofetil



The restrictions Try not to sleep during the day so you can at

night, the transplant tends to give you a strong urge for sleep. If you have pets, stay away from their vomit, urine, and stool, especially in birds. •

You can usually drive after transplant, but you need to check with transplant center first.



Try your best not to get ill.



Drinking is not aloud.

Post Operative therapy For the recipient, Post Operative care focuses on balanced immunosuppressive regimens to prevent rejection, fastidious fluid and electrolyte management, nutritional support, and prevention and treatment of infection

Large intestine closed opened

Large intestine

Works cited •

http://www.depaultulane.com/CustomPage.asp?guid http://www.umcarizona.org/body.cfm?id=983



http://www.chp.edu/cs/Satellite?blobcol=urldata&bl

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