The Immune Responses
Functions of the Immune System Defense Homeostasis Surveillance
Antigens and Antibodies Antigens
are substances not found in the
body. Most antigens are proteins.
What is an antigen?
RESPONSE TO INVASION PHAGOCYTOSIS HUMORAL CELL
IMMUNITY
MEDIATED IMMUNITY
TYPES OF IMMUNITY Natural-active
– body has to work Artificial-active – body has to work Natural-passive – body receives/no effort Artificial-passive –body receives/no effort
HUMORAL (ANTIBODIES) IMMUNE RESPONSE Allows
for rapid local or systemic reaction to antigens
Response
is to a specific antigen.
Cell-Mediated Immunity Immunity
against:
Pathogens
that survive inside cells (viruses and some bacteria) Fungal infections Rejection of transplanted tissues Tumors Contact hypersensitivity reactions
Cell Mediated Immune Response T-Helper
cells (CD4) carry the “antigen message” to the lymph nodes where they help retain the “memory” for the antigen. T-Helper cells secrete cytokines that rally other cells of the immune system.
CD8 Suppressor Cells Keep
the balance Decrease antibody reaction and prevent immune system “in check”.
HYPERSENSITIVITY REACTIONS TYPE
I
TYPE
II
TYPE
III
TYPE
IV