Formulary Updated

Commonly Used Pediatric Drugs Amoxicillin N: Treatment of infections caused by susceptible organisms eg, lower resp tract infections, UTI, skin & soft tissue infections, GI infections, upper resp tract infections, severe systemic infection D: 40 mg/kg/d q 8 hrs P: 250 mg/5 mL Cefalexin N: Treatment of susceptible infections of biliary, resp, urinary tract & skin. D: 25-50 mg/kg/d q 6 hrs P: Susp 125 mg/5 mL x 60 mL, 100 mg/5 mL x 5 mL Chloramphenicol N: Salmonella infections, shigellosis, rickettsial infection, meningitis, brain abscess & pulmonary infections, which do not respond to standard antimicrobial agents. D: 50-100 mg/kg/d q 6 hrs P: Ped susp 125 mg/5 mL x 60 mL Cloxacillin N: Staph infections including skin & soft tissue, bone & joint, resp & UTI; otitis media, endocarditis, septicemia, meningitis. Mixed strep infections. Prophylaxis of Staph infections during surgery eg cardiothoracic & orthopedic. D: 50-100 mg/kg/d q 6 hrs P: 250 mg for oral solution Co-Amoxiclav N: Treatment of variety of susceptible infections eg actinomycosis, biliary tract infections, bronchitis, endocarditis (prophylaxis), gastroenteritis (eg Salmonella enteritis), gonorrhea, Lyme disease, mouth infections, otitis media, pneumonia, spleen disorders (pneumococcal infection prophylaxis), typhoid & paratyphoid fever & UTI. Helicobacter pylori infection in patients w/ peptic ulcer. D:40 mg/kg/d q 8 hrs P: Cotrimoxazole N: Resp tract, renal, GIT, GUT. Osteomyelitis, pneumocystis carinii pneumonia, toxoplasmosis, actinomycetoma, acute brucellosis, nocardiosis, South American blastomycosis. D: 40 mg SMX & 8 mg TMP/kg/d q 12 hrs P:200 mg SMX/40 mg TMP/5 mL Diphenhydramine N: Hay fever, urticaria, vasomotor rhinitis, angioneurotic edema, drug sensitization, serum & penicillin reaction, contact dermatitis, atopic eczema, other allergic dermatoses, pruritus, food sensitivity, parkinsonism, motion sickness. D: 5 mg/kg/d q 6 hrs P: Erythromycin N: Upper & lower resp tract, skin & soft tissue infection of mild to moderate severity, other infections caused by organisms susceptible to erythromycin. D: 30 mg-50 mg/kg/day div q 8 hr PO P: Susp 200 mg/5 mL x 15 mL. Drops 100 mg/2.5 mL x 10 mL Hydroxyzine N: Symptomatic treatment of anxiety; symptomatic treatment of pruritus of allergic origin. D: 2-5 mg/kg/d q 6-8 hrs P:

Mebendazole N: Treatment of single or mixed GI worm infestations by roundworm, whipworm, hookworm, pinworm, threadworm & tapeworm. For children > 2 yrs D: 100 mg BID x 3 d; 500 mg single dose P: Metronidazole N: amebiasis D: 30-40 mg/kg/day div 3 doses P: 250 mg/5 mL Paracetamol N: Relief of fever, minor aches & pains. D: 10-15 mg/kg/dose q 4-6 hrs P: Phenylpropanolamine N: Relief of nasal congestion associated w/ common cold & other resp tract infections. D: ??? P: Syrup 6.25 mg/mL x 15 mL Pyrantel Palmoate N: Single or mixed infestations by threadworm, pinworm, roundworm, hookworm, Trichostrongylus colubriformis & orientalis. D:11 mg/kg (max: 1 g) single dose P: Rifampicin N: TB, leprosy, MRSA, serious Staph infections & other infections caused by rifampicin-sensitive organisms. D: 10-20 mg/kg/day P: Syrup 200 mg/5mL x 120 mL Salbutamol N: Treatment & prevention of bronchial asthma, bronchitis, emphysema w/ associated reversible airway obstruction. D: 0.1mg/kg/dose (max: 2 mg/dose) q 6-8 hrs P: Syrup 2 mg/5 mL x 60 mL ADULT DOSAGES Ferrous sulfate N: Iron deficiency. D: 1 cap daily. P: Vitamin B compound N: As supplements in the treatment of neuritis and polyneuritis, neuropathies, Wernicke-Korsakoff syndrome, malabsorption syndrome or metabolic disorders, drug toxicities; treatment if vit B deficiencies. D: Prophylaxis 1-2 caps daily, therapeutic 24 caps daily P: Allopurinol N: Clinical manifestations of urate/uric acid deposition eg idiopathic gout, gouty arthritis, skin tophi &/or renal involvement. Management of urate renal stones related to deficient activity of certain metabolic enzymes. Management of recurrent mixed Ca oxalate phosphate renal stones in the presence of hyperuricosuria, when fluid, dietary & similar measures have failed. D: Mild:100-200 mg daily. Moderately

severe: 300-600 mg daily. Severe: 700-900 mg daily. P: 100 mg Paracetamol N: Relief of fever, minor aches & pains. D: 1-2 tab every 4-6 hr as needed. Max: 8 tab in 24 hr. P: 250 mg, 125 mg Oral Rehydration Tablets Bisoprolol N: Treatment of stable chronic moderate to severe heart failure w/ reduced systolic ventricular function. D: 1 tab daily every morning. Max dose 10 mg P: Cotrimoxazole N: Resp tract, renal, GIT, GUT. Osteomyelitis, pneumocystis carinii pneumonia, toxoplasmosis, actinomycetoma, acute brucellosis, nocardiosis, South American blastomycosis D: 1 tab 800mg/160 mg a day or 2 tabs 400 mg/80 mg a day P: 800 mg SMX/ 160 mg TMP/cap Methyldopa N: hypertension D: 250 mg BID-TID max: 3 g daily P: 250 mg tabs Amoxicillin N: Treatment of infections caused by susceptible strains of gm+ve & gm-ve microorganisms eg actinomycosis, biliary tract, bone & joint infections, bronchitis, endocarditis, gastroenteritis, gonorrhea, mouth infections, otitis media, pneumonia, spleen disorders, typhoid & paratyphoid fever & UTI. Lyme disease. D: Cap 250-500 mg 8 hrly. P: 250 mg, 500 mg Mefenamic Acid N: Relief of pain including muscular, rheumatic, traumatic, dental, post-op & postpartum pain, headache & in childn w/ fever & juvenile RA. Also for the relief of primary dysmenorrhea. D: Cap 1 cap tid. P: 500 mg, 250 mg Diclofenac N: Inflammatory & degenerative forms of rheumatism, RA, ankylosing spondylitis, osteoarthritis, non-articular rheumatism. Acute attack of gout. Renal & biliary colic. Painful post-op inflammation & swelling-like dental & orthopedic surgery. Primary dysmenorrhea. D: Tab Initially, 100-150 mg. Long-term & milder cases 75-100 mg divided in 2-3 fractional doses. P: 50 mg Ibuprofen and Paracetamol N: Relief of mild to moderately severe pain of musculoskeletal origin eg myalgia, arthritis, rheumatism, sprain, strain, bursitis, tendonitis, backache, stiff neck, tension headache, dysmenorrhea, toothache, pain after tooth extraction & minor surgical operations, reduction of fever. D: 1 tab 6 hrly. P: 200 mg/325 mg Ambroxol

N: Resp tract diseases associated w/ abnormal bronchial secretions, particularly in exacerbations of asthmatic bronchitis & chronic bronchitis, bronchial asthma; pre- & post-op treatment. Amp Esp suitable for the prevention of pulmonary complications in intensive medicine. D: 1 tab tid P: 30 mg Ascorbic Acid N: Treatment of scurvy & in healing wounds, methemoglobinemia D: 1 tab bid-qid P: 500 mg Lagundi (Ascof) N: Relief of cough due to common cold, flu & mild to moderate acute bronchitis. Relief of reversible mild to moderate bronchospasm w/ obstructive airway disease eg asthma, chronic bronchitis & other bronchopulmonary disorders. D: 300-600 mg tid-qid. P: 300 mg Legend N: Notes (indications and adverse drug reactions) D: Dosage P: Preparations