Cytoskeleton Cytoskeleton Brief summary
The comparison of cytoskeleton Microfilaments are twisted double strands consisting of a string of proteins, from 7 nm to several cm long. The protein is actin. Its function helps muscle contraction, cell shape, and movement in cytoplasm. Intermediate filaments are made of eight subunits in rope-strands. The proteins structure varies with different tissue types. This component helps maintain shape, support nerve cell extentions, and attach cells together. Microtubules are tubes made up of spiraling, two-part subunits. It is made of tubulin. It aids in chromosome movement, movement of organelles, and the movement of cilia and flagella.
microtubule
microfilament Intermediate
component
tubulin
actin
filament monomer
diametr
25nm
7nm
10nm
structure
hollow cylinder two strands helix yes yes
rope-strands helix no
polarity
yes
No
treadmill action
sensitive
Drug action
yes Non-sensitive sensitive
The function of cytoskeleton The cytoskeleton is a dynamic structure that is responsible for whole –cell movement, changes in cell shape, contraction of muscle cells, and provides the machinery to move organelles from one place to another in the cytoplasm.
The function of microtubule 1. Microtubules are involved in intracellular vesicle and organelle transport. 2. Microtubules are composed of cilia and flagella that extend from the surfaces of several different cell types. 3. Microtubules are composed of centrosome which was one important apparatus in cell division.
The function of Microfilaments • Microfilaments are responsible for contraction in nonmuscle cells. For example, during telophase, the last stage in mitosis, a contractile ring forms on the cytoplasmic membrane surface.
The function of intermediate filament • • • •
Supporting effect, especially supporting nucleus. Transporting function, associated with microtubule and microfilament. IF affects the transporting of mRNA. IF participate in the signal transducing as a kind of information molecule.